Search
Invitrogen
Synapsin 1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 10
Synapsin 1 Antibody (51-5200) in WB
Western blot was performed using anti-Synapsin1 Polyclonal Antibody (Product # 51-5200) and 78 kDa band corresponding to Synapsin1 was observed across cell lines tested and tissues except Mouse Lung and Heart which are reported to be negative. Whole cell extracts of (30 µg lysate) of IMR-32 (Lane 1), PC-12 (Lane 2), tissue extracts of Mouse Brain (Lane 3), Mouse Lung (Lane 4) and Mouse Heart (Lane 5) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocell... View More
Product Details
51-5200
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified bovine brain Synapsin 1
Conjugate
Form
Lyophilized
Concentration
Conc. not determined
Amount
10 µg
Purification
Affinity chromatography
Storage buffer
5mM Ammonium bicarbonate
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody should be reconstituted in 50 uL phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After reconstitution the antibody should be aliquot and stored at -20C.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Brain protein 4.1; synapsin 1; Synapsin I; synapsin Ib; Synapsin-1; truncated synapsin 1-S
Gene Aliases: EPILX; EPILX1; MRX50; Syn-1; SYN1; Syn1-S; SYN1a; SYN1b; SYNI
UniProt ID: (Human) P17600, (Bovine) P17599, (Rat) P09951, (Mouse) O88935
Entrez Gene ID: (Human) 6853, (Bovine) 281510, (Rat) 24949, (Mouse) 20964
chemical synaptic transmission
neurotransmitter secretion
regulation of neurotransmitter secretion
neuron development
modulation of synaptic transmission
synapse organization
synaptic vesicle clustering
regulation of synaptic vesicle cycle
synaptic vesicle cycle
regulation of synaptic vesicle exocytosis
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support