|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 229 of 53BP1 (Uniprot ID#Q12888)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34675 targets 53BP1 in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-34675 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 229 of 53BP1 (Uniprot ID#Q12888).
Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.