The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT3-C; 5-HT3C; 5-hydroxytryptamine (serotonin) receptor 3, family member C; 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic; 5-hydroxytryptamine receptor 3 subunit C; 5-hydroxytryptamine receptor 3C; Serotonin receptor 3C
Gene Aliases: HTR3C
UniProt ID: (Human) Q8WXA8
Entrez Gene ID: (Human) 170572
Molecular Function: ligand-gated ion channel