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5HT4 R Polyclonal Antibody
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FIGURE: 1 / 9
5HT4 R Antibody (OSS00421W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse spleen. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candela DAB chromogen ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
OSS00421W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from human 5HT4 R conjugated to blue carrier protein was used as the antigen
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: 5HT4 receptor.
Target Information
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-HT-4; 5-HT4 receptor; 5-hydroxytryptamine receptor 4; 5HT4; 5HT4 receptor; Serotonin receptor 4
Gene Aliases: 5-HT-4; 5-HT4; 5-HT<4L>; 5HTR4; HTR4
UniProt ID: (Mouse) P97288
Entrez Gene ID: (Mouse) 15562
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
regulation of appetite
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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