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5HT6 Receptor/SR-6 Polyclonal Antibody
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Product Details
BS-12058R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human 5HT6 Receptor/SR-6, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This is one of the several different receptors for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-HT-6; 5-HT6; 5-HT6 receptor; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; 5-hydroxytryptamine receptor 6; G-protein coupled receptor; HTR6; Serotonin receptor 6; ST-B17
Gene Aliases: 5-HT6; 5-HT6R; HTR6
UniProt ID: (Human) P50406, (Mouse) Q9R1C8
Entrez Gene ID: (Human) 3362, (Mouse) 15565, (Rat) 64354
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating serotonin receptor signaling pathway
chemical synaptic transmission
positive regulation of cell communication
cerebral cortex cell migration
positive regulation of signaling
positive regulation of TOR signaling
G protein-coupled serotonin receptor signaling pathway
serotonin receptor signaling pathway
learning
negative regulation of glutamate secretion
negative regulation of gamma-aminobutyric acid secretion
positive regulation of gamma-aminobutyric acid secretion
negative regulation of acetylcholine secretion, neurotransmission
positive regulation of dopamine secretion
long-term synaptic potentiation
brain development
response to estradiol
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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