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Proteintech
STOML2 Monoclonal Antibody (1A2E9)
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Product Details
60052-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1A2E9
Immunogen
STOML2 Fusion Protein Ag0363 (81-356 aa encoded by BC002442)
Conjugate
Form
Liquid
Concentration
1.07 mg/mL
Amount
160.5 µg
Purification
Caprylic acid precipitation
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EIVINVPEQ SAVTLDNVTL QIDGVLYLRI MDPYKASYGV EDPEYAVTQL AQTTMRSELG KLSLDKVFRE RESLNASIVD AINQAADCWG IRCLRYEIKD IHVPPRVKES MQMQVEAERR KRATVLESEG TRESAINVAE GKKQAQILAS EAEKAEQINQ AAGEASAVLA KAKAKAEAIR ILAAALTQHN GDAAASLTVA EQYVSAFSKL AKDSNTILLP SNPGDVTSMV AQAMGVYGAL TKAPVPGTPD SLSSGSSRDV QGTDASLDEE LDRVKMS (81-356 aa encoded by BC002442)
Target Information
Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EPB72-like 2; EPB72-like protein 2; Paraprotein target 7; Paratarg-7; SLP-2; stomatin (EPB72)-like 2; stomatin-like protein 2; Stomatin-like protein 2, mitochondrial; unnamed protein product
Gene Aliases: 0610038F01Rik; HSPC108; MSLP2; SLP-2; SLP2; STOML2
UniProt ID: (Human) Q9UJZ1, (Mouse) Q99JB2, (Rat) Q4FZT0
Entrez Gene ID: (Pig) 100625031, (Human) 30968, (Mouse) 66592, (Rat) 298203
cellular calcium ion homeostasis
mitochondrion organization
lipid localization
positive regulation of interleukin-2 production
mitochondrial protein processing
CD4-positive, alpha-beta T cell activation
mitochondrial ATP synthesis coupled proton transport
T cell receptor signaling pathway
protein oligomerization
stress-induced mitochondrial fusion
mitochondrial calcium ion transport
positive regulation of mitochondrial membrane potential
interleukin-2 production
mitochondrion localization
positive regulation of mitochondrial DNA replication
positive regulation of cardiolipin metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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