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GMF-beta Monoclonal Antibody (3B10A2)
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Product Details
60062-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3B10A2
Immunogen
GMF-beta Fusion Protein Ag1104 (1-154 aa encoded by BC005359)
Conjugate
Form
Liquid
Concentration
0.68 mg/mL
Amount
102 µg
Purification
Caprylic acid precipitation
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSESLVVCD VAEDLVEKLR KFRFRKETNN AAIIMKIDKD KRLVVLDEEL EGISPDELKD ELPERQPRFI VYSYKYQHDD GRVSYPLCFI FSSPVGCKPE QQMMYAGSKN KLVQTAELTK VFEIRNTEDL TEEWLREKLG FFTNVNFCVS KVFMY (1-154 aa encoded by BC005359)
Target Information
This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF; being produced by the tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Glia maturation factor beta; GMF-beta; GMFB; unnamed protein product
Gene Aliases: GMF; GMFB
UniProt ID: (Human) P60983
Entrez Gene ID: (Human) 2764, (Pig) 100625819
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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