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Proteintech
EEF1D Monoclonal Antibody (3B1B11)
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Product Details
60085-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3B1B11
Immunogen
EEF1D Fusion Protein Ag0983 (347-647 aa encoded by BC007847)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Caprylic acid precipitation
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The calculated molecular weight of EEF1D is 31 kDa, but the modified protein is about 35-40 kDa.
Immunogen sequence: SHRPGPRSG LSVSSLRPNR KMATNFLAHE KIWFDKFKYD DAERRFYEQM NGPVAGASRQ ENGASVILRD IARARENIQK SLAGSSGPGA SSGTSGDHGE LVVRIASLEV ENQSLRGVVQ ELQQAISKLE ARLNVLEKSS PGHRATAPQT QHVSPMRQVE PPAKKPATPA EDDEDDDIDL FGSDNEEEDK EAAQLREERL RQYAEKKAKK PALVAKSSIL LDVKPWDDET DMAQLEACVR SIQLDGLVWG ASKLVPVGYG IRKLQIQCVV EDDKVGTDLL EEEITKFEEH VQSVDIAAFN KI (347-647 aa encoded by BC007847)
Target Information
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Antigen NY-CO-4; EEF 1D; EF 1 delta; EF 1D; EF-1-delta; Elongation factor 1-delta; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); guanine nucleotide exchange protein; translation elongation factor 1-delta subunit; unnamed protein product
Gene Aliases: EEF1D; EF-1-delta; EF-1D; EF1D; FP1047; NEDTCHAL
UniProt ID: (Human) P29692, (Mouse) P57776, (Rat) Q68FR9
Entrez Gene ID: (Human) 1936, (Mouse) 66656, (Rat) 300033
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
translation elongation factor activity
guanyl-nucleotide exchange factor activity
protein binding
translation factor activity, RNA binding
heat shock protein binding
cadherin binding
DNA-binding transcription factor binding
signal transducer activity
activating transcription factor binding
translation elongation factor
cytoplasmic translational elongation
translation
translational elongation
cellular response to heat
positive regulation of transcription from RNA polymerase II promoter
cellular response to ionizing radiation
transcription, DNA-templated
regulation of transcription, DNA-templated
signal transduction
mRNA transcription
regulation of cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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