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Proteintech
DBC1 Monoclonal Antibody (2A10E3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
60336-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Mouse
/ IgG2c
Class
Monoclonal
Type
Antibody
Clone
2A10E3
Immunogen
DBC1 Fusion Protein Ag6588 (1-320 aa encoded by BC021560)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.57 mg/mL
Amount
235.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNWRFVELL YFLFIWGRIS VQPSHQEPAG TDQHVSKEFD WLISDRGPFH HSRSYLSFVE RHRQGFTTRY KIYREFARWK VRNTAIERRD LVRHPVPLMP EFQRSIRLLG RRPTTQQFID TIIKKYGTHL LISATLGGEE ALTMYMDKSR LDRKSGNATQ SVEALHQLAS SYFVDRDGTM RRLHEIQIST GAIKVTETRT GPLGCNSYDN LDSVSSVLLQ STESKLHLQG LQIIFPQYLQ EKFVQSALSY IMCNGEGEYL CQNSQCRCQC AEEFPQCNCP ITDIQIMEYT LANMAKSWAE AYKDLEN (1-320 aa encoded by BC021560)
Target Information
This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bA574M5.1 (deleted in bladder cancer chromosome region candidate 1 (IB3089A)); BMP/retinoic acid-inducible neural-specific protein (BRINP); bone morphogenetic protein/retinoic acid inducible neural-specific 1; bone morphogenic protein/retinoic acid inducible neural-specific 1; deleted in bladder cancer 1; deleted in bladder cancer chromosome region 1; deleted in bladder cancer chromosome region candidate 1; deleted in bladder cancer protein 1; deleted in bladder cancer protein 1 homolog; unnamed protein product
Gene Aliases: BRINP; DBC1; DBCCR1; FAM5A
UniProt ID: (Human) O60477, (Mouse) Q920P3
Entrez Gene ID: (Human) 1620, (Pig) 100625235, (Mouse) 56710
brain development
central nervous system neuron differentiation
central nervous system neuron development
positive regulation of neuron differentiation
negative regulation of mitotic cell cycle
cellular response to retinoic acid
behavioral fear response
short-term memory
cell proliferation
gene expression
proteasomal protein catabolic process
social behavior
exploration behavior
maternal behavior
negative regulation of cell cycle
homeostasis of number of cells within a tissue
negative regulation of neurogenesis
protein stabilization
vocalization behavior
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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