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          • Primary Antibodies ›
          • IVD Antibodies

          Proteintech

          IVD Monoclonal Antibody (2D12A5)

          1 Reference
          View all (20) IVD antibodies

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          Cite IVD Monoclonal Antibody (2D12A5)

          Additional Information:
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          • Antibody Testing Data (14)
          IVD Antibody in Immunocytochemistry (ICC/IF)
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          IVD Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 14

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          IVD Antibody (66032-1-IG) in ICC/IF

          Immunofluorescent analysis of MCF-7 cells, using IVD antibody 66032-1-Ig at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          IVD Antibody in Immunocytochemistry (ICC/IF)
          IVD Antibody in Immunocytochemistry (ICC/IF)
          IVD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IVD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IVD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IVD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IVD Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          IVD Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          IVD Antibody in Western Blot (WB)
          IVD Antibody in Western Blot (WB)
          IVD Antibody in Western Blot (WB)
          IVD Antibody in Western Blot (WB)
          IVD Antibody in Western Blot (WB)
          IVD Antibody in Western Blot (WB)
          IVD Monoclonal Antibody (2D12A5)

          Product Details

          66032-1-IG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:6,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          Rat

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          2D12A5

          Immunogen

          IVD Fusion Protein Ag18042 (1-423 aa encoded by BC017202)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • CoraLite 594
          • Request custom conjugation

          Form

          Liquid

          Concentration

          0.64 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MATATRLLG CRVASWRLRP PLAGFVSQRA HSLLPVDDAI NGLSEEQRQL RQTMAKFLQE HLAPKAQEID RSNEFKNLRE FWKQLGNLGV LGITAPVQYG GSGLGYLEHV LVMEEISRAS GAVGLSYGAH SNLCINQLVR NGNEAQKEKY LPKLISGEYI GALAMSEPNA GSDVVSMKLK AEKKGNHYIL NGNKFWITNG PDADVLIVYA KTDLAAVPAS RGITAFIVEK GMPGFSTSKK LDKLGMRGSN TCELIFEDCK IPAANILGHE NKGVYVLMSG LDLERLVLAG GPLGLMQAVL DHTIPYLHVR EAFGQKIGHF QLMQGKMADM YTRLMACRQY VYNVAKACDE GHCTAKDCAG VILYSAECAT QVALDGIQCF GGNGYINDFP MGRFLRDAKL YEIGAGTSEV RRLVIGRAFN ADFH (1-423 aa encoded by BC017202)

          Target Information

          Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Butyryl-CoA dehydrogenase; epididymis secretory sperm binding protein; GIG48a; GIG48b; GIG48c; isovaleryl Coenzyme A dehydrogenase; isovaleryl-coA dehydrogenase (IVD); Isovaleryl-CoA dehydrogenase, mitochondrial; IVD; organic acid metabolism; unnamed protein product

          View more View less

          Gene Aliases: ACAD2; IVD; IVDH

          View more View less

          UniProt ID: (Human) P26440

          View more View less

          Entrez Gene ID: (Human) 3712

          View more View less

          Function(s)
          acyl-CoA dehydrogenase activity protein binding isovaleryl-CoA dehydrogenase activity oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors short-branched-chain-acyl-CoA dehydrogenase activity identical protein binding flavin adenine dinucleotide binding
          Process(es)
          leucine catabolic process lipid metabolic process fatty acid metabolic process branched-chain amino acid catabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase
          It has to be done as per old AB suggested Products section.

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