Search
Proteintech
CUL4A Monoclonal Antibody (1A7F12)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
66038-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Pig,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A7F12
Immunogen
CUL4A Fusion Protein Ag18089 (460-759 aa encoded by BC008308)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.76 mg/mL
Amount
114 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RLLVGKSAS VDAEKSMLSK LKHECGAAFT SKLEGMFKDM ELSKDIMVHF KQHMQNQSDS GPIDLTVNIL TMGYWPTYTP MEVHLTPEMI KLQEVFKAFY LGKHSGRKLQ WQTTLGHAVL KAEFKEGKKE FQVSLFQTLV LLMFNEGDGF SFEEIKMATG IEDSELRRTL QSLACGKARV LIKSPKGKEV EDGDKFIFNG EFKHKLFRIK INQIQMKETV EEQVSTTERV FQDRQYQIDA AIVRIMKMRK TLGHNLLVSE LYNQLKFPVK PGDLKKRIES LIDRDYMERD KDNPNQYHYV A (460-759 aa encoded by BC008308)
Target Information
CUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CUL 4A; CUL-4A; Cul4a protein; MGC36573; MGC64071; OTTHUMP00000018753; ubiquitin E3 ligase; unnamed protein product
Gene Aliases: 2810470J21Rik; RGD1563853
UniProt ID: (Human) Q13619, (Mouse) Q3TCH7
Entrez Gene ID: (Pig) 100517912, (Human) 8451, (Mouse) 99375, (Rat) 361181
G1/S transition of mitotic cell cycle
in utero embryonic development
nucleotide-excision repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
spermatogenesis
cell proliferation
regulation of autophagy
protein ubiquitination
regulation of DNA-dependent DNA replication initiation
replication fork processing
developmental process
regulation of natural killer cell activation
cellular response to UV
regulation of gene expression, epigenetic
T cell activation
regulation of cell proliferation
ribosome biogenesis
regulation of apoptotic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
regulation of embryonic development
regulation of protein metabolic process
regulation of gene silencing by miRNA
regulation of cellular response to stress
intrinsic apoptotic signaling pathway
ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
regulation of cell cycle phase transition
regulation of mitotic cytokinesis
negative regulation of adipose tissue development
regulation of stem cell population maintenance
positive regulation of cell proliferation
hemopoiesis
negative regulation of granulocyte differentiation
somatic stem cell population maintenance
mRNA cleavage involved in gene silencing by miRNA
type I interferon signaling pathway
base-excision repair, AP site formation via deaminated base removal
positive regulation of G1/S transition of mitotic cell cycle
regulation of DNA damage checkpoint
regulation of nucleotide-excision repair
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support