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RACGAP1 Monoclonal Antibody (6E10A2)

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RACGAP1 Monoclonal Antibody (6E10A2)

Product Details

66056-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunocytochemistry (ICC/IF)

1:20-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6E10A2

Immunogen

RACGAP1 Fusion Protein Ag6944 (334-632 aa encoded by BC032754)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

150 µg

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: PCIPTLIGT PVKIGEGMLA DFVSQTSPMI PSIVVHCVNE IEQRGLTETG LYRISGCDRT VKELKEKFLR VKTVPLLSKV DDIHAICSLL KDFLRNLKEP LLTFRLNRAF MEAAEITDED NSIAAMYQAV GELPQANRDT LAFLMIHLQR VAQSPHTKMD VANLAKVFGP TIVAHAVPNP DPVTMLQDIK RQPKVVERLL SLPLEYWSQF MMVEQENIDP LHVIENSNAF STPQTPDIKV SLLGPVTTPE HQLLKTPSSS SLSQRVRSTL TKNTPRFGSK SKSATNLGRQ GNFFASPMLK (334-632 aa encoded by BC032754)

Target Information

RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AKT; CYK4; GAP; ID; Male germ cell RacGap; MGC99656; MgcRacGAP; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase-activating protein 1; RAC-ALPHA; RACGAP1; unnamed protein product

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Gene Aliases: AI227039; AI327394; Band25; CDAN3B; CYK4; gtl11; GTPase; HsCYK-4; ID-GAP; KIAA1478; MGCRACGAP; mKIAA1478; RACGAP1; RCGAP1

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UniProt ID: (Human) Q9H0H5, (Mouse) Q9WVM1

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Entrez Gene ID: (Human) 29127, (Mouse) 26934, (Rat) 315298

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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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