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Proteintech
EPLIN Monoclonal Antibody (6E6E6)
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Product Details
66071-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6E6E6
Immunogen
EPLIN Fusion Protein Ag13288 (261-401 aa encoded by BC001247)
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes both of isoforms of EPLN.
Immunogen sequence: KPLSPDSRA SSLSESSPPK AMKFQAPARE TCVECQKTVY PMERLLANQQ VFHISCFRCS YCNNKLSLGT YASLHGRIYC KPHFNQLFKS KGNYDEGFGH RPHKDLWASK NENEEILERP AQLANARETP HSPGVEDAPI AK (261-401 aa encoded by BC001247)
Target Information
EPLIN is a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Epithelial protein lost in neoplasm; epithelial protein lost in neoplasm beta; EPLIN; LIM domain and actin-binding protein 1; sterol regulatory element binding protein 3; unnamed protein product
Gene Aliases: EPLIN; LDLCQ8; LIMA1; PP624; SREBP3
UniProt ID: (Human) Q9UHB6, (Rat) F1LR10
Entrez Gene ID: (Human) 51474, (Rat) 300228
lipid metabolic process
steroid metabolic process
cholesterol metabolic process
cell migration
intestinal cholesterol absorption
negative regulation of cell migration
negative regulation of actin filament depolymerization
ruffle organization
positive regulation of actin filament bundle assembly
cholesterol homeostasis
actin filament bundle assembly
negative regulation of cilium assembly
regulation of lamellipodium organization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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