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Proteintech
RBP4 Monoclonal Antibody (1D12B11)
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Product Details
66104-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1D12B11
Immunogen
RBP4 Fusion Protein Ag19295 (1-201 aa encoded by BC020633)
Conjugate
Form
Liquid
Concentration
1.21 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKWVWALFL LAALGSGRAE RDCRVSSFRV KENFDKARFS GTWYAMAKKD PEGLFLQDNI VAEFSVDETG QMSATAKGRV RLLNNWDVCA DMVGTFTDTE DPAKFKMKYW GVASFLQKGN DDHWIVDTDY DTYAVQYSCR LLNLDGTCAD SYSFVFSRDP NGLPPEAQKI VRQRQEELCL ARQYRLIVHN GYCDGRSERN LL (1-201 aa encoded by BC020633)
Target Information
This protein belongs to the lipocalin family and is the specific carrier for retinol in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post translationally and results in defective delivery and supply to the epidermal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Plasma retinol binding protein 4 (PRBP); Plasma retinol-binding protein; PRBP; RBP; retinol; retinol binding; Retinol binding protein 4 interstitial; retinol binding protein 4, plasma; Retinol-binding protein 4; retinol-binding protein 4, interstitial; unnamed protein product
Gene Aliases: MCOPCB10; PRO2222; RBP4; RDCCAS
UniProt ID: (Human) P02753
Entrez Gene ID: (Human) 5950
retinoid metabolic process
eye development
positive regulation of immunoglobulin production
gluconeogenesis
spermatogenesis
heart development
visual perception
phototransduction, visible light
male gonad development
response to xenobiotic stimulus
response to muscle activity
maintenance of gastrointestinal epithelium
lung development
positive regulation of insulin secretion
response to retinoic acid
response to insulin
retinol transport
retinol metabolic process
retinal metabolic process
glucose homeostasis
response to ethanol
embryonic organ morphogenesis
embryonic skeletal system development
cardiac muscle tissue development
female genitalia morphogenesis
detection of light stimulus involved in visual perception
retina development in camera-type eye
negative regulation of cardiac muscle cell proliferation
embryonic retina morphogenesis in camera-type eye
uterus development
vagina development
urinary bladder development
heart trabecula formation
vitamin A import
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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