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Proteintech

TBP Monoclonal Antibody (2H3B2)

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TBP Monoclonal Antibody (2H3B2)

Product Details

66166-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:16,000
View 19 publications 19 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:325-1:1300
-

Immunocytochemistry (ICC/IF)

1:50-1:500
View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells
-

Immunoprecipitation (IP)

0.5-4.0 µg
-

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Published species

Human, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

2H3B2

Immunogen

TBP Fusion Protein Ag12383 (1-338 aa encoded by BC110341)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Amount

225 µg

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody detects human TBP (~40 kDa) and mouse/rat Tbp (~35 kDa).

Immunogen sequence: MDQNNSLPP YAQGLASPQG AMTPGIPIFS PMMPYGTGLT PQPIQNTNSL SILEEQQRQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQAVAAA AVQQSTSQQA TQGTSGQAPQ LFHSQTLTTA PLPGTTPLYP SPMTPMTPIT PATPASESSG IVPQLQNIVS TVNLGCKLDL KTIALRARNA EYNPKRFAAV IMRIREPRTT ALIFSSGKMV CTGAKSEEQS RLAARKYARV VQKLGFPAKF LDFKIQNMVG SCDVKFPIRL EGLVLTHQQF SSYEPELFPG LIYRMIKPRI VLLIFVSGKV VLTGAKVRAE IYEAFENIYP ILKGFRKTT (1-338 aa encoded by BC110341 )

Target Information

RICH1 is a GTPase-activating protein (GAP). GAPs stimulate the intrinsic GTP hydrolysis of small G proteins, such as RHOA, RAC1, and CDC42.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: MGC117320; MGC126054; MGC126055; RP1-191N21.3; TATA sequence-binding protein; TATA-binding factor; TATA-binding protein; TATA-box binding protein N-terminal domain; TATA-box factor; tata-box-binding; TATA-box-binding protein; TBP; TFIID; TFIID core protein; Transcription initiation factor TFIID TBP subunit; unnamed protein product

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Gene Aliases: GTF2D; GTF2D1; HDL4; SCA17; TBP; TBP1; TF2D; TFIID

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UniProt ID: (Human) P20226, (Mouse) P29037

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Entrez Gene ID: (Pig) 110259740, (Human) 6908, (Mouse) 21374, (Rat) 117526

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Function(s)
transcription regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, core RNA polymerase III binding core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor binding TFIIB-class transcription factor binding RNA polymerase I CORE element sequence-specific DNA binding DNA binding protein binding obsolete general RNA polymerase II transcription factor activity aryl hydrocarbon receptor binding enzyme binding RNA polymerase II sequence-specific DNA binding transcription factor binding DNA-binding transcription factor binding RNA polymerase II repressing transcription factor binding transcription factor activity, sequence-specific DNA binding transcription factor binding transcription regulatory region DNA binding repressing transcription factor binding general transcription factor
Process(es)
RNA polymerase I preinitiation complex assembly DNA-templated transcription, initiation transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter transcription from RNA polymerase III promoter spermatogenesis mRNA transcription from RNA polymerase II promoter positive regulation of transcription, DNA-templated RNA polymerase II transcriptional preinitiation complex assembly positive regulation of transcription initiation from RNA polymerase II promoter transcription, DNA-templated regulation of transcription, DNA-templated
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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