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MPO Monoclonal Antibody (4C11F6)
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Product Details
66177-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgA
Class
Monoclonal
Type
Antibody
Clone
4C11F6
Immunogen
MPO Fusion Protein Ag17564 (606-657 aa encoded by BC130476)
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Amount
105 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CGLPQPETV GQLGTVLRNL KLARKLMEQY GTPNNIDIWM GGVSEPLKRK GRV (606-657 aa encoded by BC130476)
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MPO; Myeloperoxidase; unnamed protein product
Gene Aliases: MPO
UniProt ID: (Human) P05164
Entrez Gene ID: (Human) 4353, (Rat) 303413
response to yeast
hypochlorous acid biosynthetic process
respiratory burst involved in defense response
defense response
response to oxidative stress
response to mechanical stimulus
removal of superoxide radicals
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
defense response to bacterium
hydrogen peroxide catabolic process
negative regulation of apoptotic process
defense response to fungus
response to gold nanoparticle
aging
negative regulation of growth of symbiont in host
defense response to Gram-positive bacterium
oxidation-reduction process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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