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Proteintech
SERPINE2 Monoclonal Antibody (1E11F12)
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Product Details
66203-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E11F12
Immunogen
SERPINE2 Fusion Protein Ag1830 (28-397 aa encoded by BC015663)
Conjugate
Form
Liquid
Concentration
0.87 mg/mL
Amount
130.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EELGSNTGI QVFNQIVKSR PHDNIVISPH GIASVLGMLQ LGADGRTKKQ LAMVMRYGVN GVGKILKKIN KAIVSKKNKD IVTVANAVFV KNASEIEVPF VTRNKDVFQC EVRNVNFEDP ASACDSINAW VKNETRDMID NLLSPDLIDG VLTRLVLVNA VYFKGLWKSR FQPENTKKRT FVAADGKSYQ VPMLAQLSVF RCGSTSAPND LWYNFIELPY HGESISMLIA LPTESSTPLS AIIPHISTKT IDSWMSIMVP KRVQVILPKF TAVAQTDLKE PLKVLGITDM FDSSKANFAK ITTGSENLHV SHILQKAKIE VSEDGTKASA ATTAILIARS SPPWFIVDRP FLFFIRHNPT GAVLFMGQIN K (28-397 aa encoded by BC015663)
Target Information
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GDN; Glia derived nexin; Glia-derived nexin; glia-derived nexin precursor; Glia-derived nexin/protease nexin I; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; plasminogen activator inhibitor type 1; PN-1; Protease nexin 1; Protease nexin I; protease nexin PN-1; serine (or cysteine) peptidase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serpin peptidase inhibitor, clade E, member 2; SERPINE 2; unnamed protein product
Gene Aliases: B230326M24Rik; GDN; GDNPF; Gdnpn1; PAI-1; PI-7; PI7; PN-1; PN1; PNI; SERPINE2; Spi4; Spin4
UniProt ID: (Human) P07093, (Rat) P07092, (Mouse) Q07235
Entrez Gene ID: (Human) 5270, (Rat) 29366, (Mouse) 20720
nervous system development
blood coagulation
negative regulation of cell proliferation
response to wounding
negative regulation of platelet activation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of protein processing
cerebellar granular layer morphogenesis
cell differentiation
protein catabolic process
platelet activation
negative regulation of blood coagulation
negative regulation of cell growth
regulation of cell migration
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
negative regulation of protein kinase B signaling
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
negative regulation of platelet aggregation
embryo implantation
response to radiation
negative regulation of peptidase activity
negative regulation of endopeptidase activity
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
dense core granule biogenesis
multicellular organism development
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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