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Apolipoprotein AI Monoclonal Antibody (1C9G5)

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View all (48) ApoA1 antibodies

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Apolipoprotein AI Monoclonal Antibody (1C9G5)

Product Details

66206-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:4,000
View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:500
-

Flow Cytometry (Flow)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse

Published species

Mouse

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

1C9G5

Immunogen

Apolipoprotein AI Fusion Protein Ag21920 (19-267 aa encoded by BC005380)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.07 mg/mL

Amount

160.5 µg

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody was generated against the C-terminal region of human ApoA1.

Immunogen sequence: RHFWQQDEP PQSPWDRVKD LATVYVDVLK DSGRDYVSQF EGSALGKQLN LKLLDNWDSV TSTFSKLREQ LGPVTQEFWD NLEKETEGLR QEMSKDLEEV KAKVQPYLDD FQKKWQEEME LYRQKVEPLR AELQEGARQK LHELQEKLSP LGEEMRDRAR AHVDALRTHL APYSDELRQR LAARLEALKE NGGARLAEYH AKATEHLSTL SEKAKPALED LRQGLLPVLE SFKVSFLSAL EEYTKKLNTQ (19-267 aa encoded by BC005380)

Target Information

Apolipoprotein A-1 (apo A-1) in human plasma is a major protein component of high density lipoprotein (HDL). The molecular mass is 24 kDa. Apo A-1 is a cofactor for enzymes involved in the normal turnover of cholesterol and is produced in the liver. Plasma concentration is 270-380 mg/100 mL.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 1-Sep; 2-Sep; Apo a; apo A-1; APO A1; APO I; Apo-AI; ApoAI; Apolipoprotein; Apolipoprotein A-I; Apolipoprotein A1; Apolipoprotein AI; epididymis secretory sperm binding protein; MGC102525; MGC117399; MGC124929; proapo-A-I protein; proapolipoprotein; Udpgt; Ugt1; Ugt1a7; unnamed protein product

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Gene Aliases: Alp-1; AMYLD3; apo(a); apo-AI; Apoa-1; apoA-I; APOA1; Brp-14; HPALP2; Ltw-1; Lvtw-1; Sep-1; Sep-2; Sep2

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UniProt ID: (Human) P02647, (Mouse) Q00623

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Entrez Gene ID: (Human) 335, (Mouse) 11806

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Function(s)
beta-amyloid binding receptor binding lipid transporter activity protein binding phospholipid binding high-density lipoprotein particle binding lipid binding cholesterol binding enzyme binding heat shock protein binding apolipoprotein receptor binding apolipoprotein A-I receptor binding identical protein binding protein homodimerization activity chemorepellent activity receptor agonist activity phosphatidylcholine-sterol O-acyltransferase activator activity high-density lipoprotein particle receptor binding lipoprotein particle binding intermembrane cholesterol transfer activity phospholipid transporter activity cholesterol transporter activity phosphatidylcholine binding lipase inhibitor activity apolipoprotein
Process(es)
endothelial cell proliferation negative regulation of cytokine production involved in immune response lipid metabolic process phospholipid metabolic process phosphatidylcholine biosynthetic process cholesterol biosynthetic process lipid transport transforming growth factor beta receptor signaling pathway G-protein coupled receptor signaling pathway integrin-mediated signaling pathway steroid metabolic process cholesterol metabolic process glucocorticoid metabolic process negative regulation of tumor necrosis factor-mediated signaling pathway positive regulation of cholesterol efflux negative regulation of very-low-density lipoprotein particle remodeling protein oxidation peptidyl-methionine modification lipid storage regulation of intestinal cholesterol absorption cholesterol transport adrenal gland development regulation of Cdc42 protein signal transduction negative regulation of interleukin-1 beta production cholesterol efflux phospholipid efflux negative regulation of heterotypic cell-cell adhesion beta-amyloid formation high-density lipoprotein particle remodeling high-density lipoprotein particle assembly high-density lipoprotein particle clearance positive regulation of Rho protein signal transduction lipoprotein metabolic process lipoprotein biosynthetic process cholesterol homeostasis blood vessel endothelial cell migration reverse cholesterol transport negative regulation of inflammatory response positive regulation of phagocytosis protein stabilization negative chemotaxis vitamin transport positive regulation of stress fiber assembly acylglycerol homeostasis phospholipid homeostasis negative regulation of cell adhesion molecule production negative regulation of response to cytokine stimulus triglyceride homeostasis ERK1 and ERK2 cascade cholesterol import cellular response to lipoprotein particle stimulus positive regulation of cholesterol metabolic process positive regulation of substrate adhesion-dependent cell spreading positive regulation of phospholipid efflux cellular response to beta-amyloid regulation of protein phosphorylation negative regulation of cytokine secretion involved in immune response transport protein localization positive regulation of cholesterol esterification positive regulation of triglyceride catabolic process phospholipid transport triglyceride catabolic process organ regeneration axon regeneration very-low-density lipoprotein particle remodeling positive regulation of fatty acid biosynthetic process phosphatidylcholine metabolic process negative regulation of interleukin-1 beta secretion positive regulation of lipoprotein lipase activity positive regulation of hydrolase activity negative regulation of hydrolase activity positive regulation of transferase activity negative regulation of lipase activity
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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