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Proteintech
CD68 Monoclonal Antibody (3A9A7)
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Product Details
66231-2-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3A9A7
Immunogen
CD68 Fusion Protein Ag22815 (29-319 aa encoded by BC015557)
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Amount
151.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SATLLPSFT VTPTVTESTG TTSHRTTKSH KTTTHRTTTT GTTSHGPTTA THNPTTTSHG NVTVHPTSNS TATSQGPSTA THSPATTSHG NATVHPTSNS TATSPGFTSS AHPEPPPPSP SPSPTSKETI GDYTWTNGSQ PCVHLQAQIQ IRVMYTTQGG GEAWGISVLN PNKTKVQGSC EGAHPHLLLS FPYGHLSFGF MQDLQQKVVY LSYMAVEYNV SFPHAAQWTF SAQNASLRDL QAPLGQSFSC SNSSIILSPA VHLDLLSLRL QAAQLPHTGV FGQSFSCPSD RS (29-319 aa encoded by BC015557)
Target Information
CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 110kda transmembrane glycoprotein; CD68; CD68 antigen; Gp110; macrophage antigen CD68; Macrosialin; scavenger receptor class D, member 1; unnamed protein product
Gene Aliases: CD68; GP110; LAMP4; SCARD1
UniProt ID: (Human) P34810
Entrez Gene ID: (Human) 968
inflammatory response to antigenic stimulus
negative regulation of dendritic cell antigen processing and presentation
cellular response to nutrient levels
autocrine signaling
response to ethanol
cellular response to lipopolysaccharide
establishment of protein localization to organelle
cellular response to oxidised low-density lipoprotein particle stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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