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Proteintech
Fascin Monoclonal Antibody (1B5G3)
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Product Details
66321-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1B5G3
Immunogen
Fascin Fusion Protein Ag6074 (1-187 aa encoded by BC000521)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTANGTAEA VQIQFGLINC GNKYLTAEAF GFKVNASASS LKKKQIWTLE QPPDEAGSAA VCLRSHLGRY LAADKDGNVT CEREVPGPDC RFLIVAHDDG RWSLQSEAHR RYFGGTEDRL SCFAQTVSPA EKWSVHIAMH PQVNIYSVTR KRYAHLSARP ADEIAVDRDV PWGVDSLITL AFQDQRYS (1-187 aa encoded by BC000521)
Target Information
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; epididymis secretory sperm binding protein; Fascin; Fascin homolog 1; fascin homolog 1, actin-bundling protein; Fascin1; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein; unnamed protein product
Gene Aliases: FAN1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658
Entrez Gene ID: (Human) 6624
actin filament organization
cell-cell junction assembly
establishment or maintenance of cell polarity
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
parallel actin filament bundle assembly
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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