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Proteintech
CAPRIN1 Monoclonal Antibody (6B10F11)
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Product Details
66352-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6B10F11
Immunogen
CAPRIN1 Fusion Protein Ag7413 (356-709 aa encoded by BC001731)
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Amount
111 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RQRVQDLMA QMQGPYNFIQ DSMLDFENQT LDPAIVSAQP MNPTQNMDMP QLVCPPVHSE SRLAQPNQVP VQPEATQVPL VSSTSEGYTA SQPLYQPSHA TEQRPQKEPI DQIQATISLN TDQTTASSSL PAASQPQVFQ AGTSKPLHSS GINVNAAPFQ SMQTVFNMNA PVPPVNEPET LKQQNQYQAS YNQSFSSQPH QVEQTELQQE QLQTVVGTYH GSPDQSHQVT GNHQQPPQQN TGFPRSNQPY YNSRGVSRGG SRGARGLMNG YRGPANGFRG GYDGYRPSFS NTPNSGYTQS QFSAPRDYSG YQRDGYQQNF KRGSGQSGPR GAPRGRGGPP RPNRGMPQMN TQQVN (356-709 aa encoded by BC001731)
Target Information
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activation/proliferation-associated protein 1; caprin 1; Caprin-1; Cell cycle-associated protein 1; cytop; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; Membrane component chromosome 11 surface marker 1; p137GPI; RNA granule protein 105; unnamed protein product
Gene Aliases: AL022980; Caprin-1; CAPRIN1; CONDCAC; G5E5; GPI p137; Gpiap; GPIAP1; GPIP137; GRIP137; M11S1; Mmgpip137; NEDLAAD; P137; p137GPI; RNG105
UniProt ID: (Human) Q14444, (Mouse) Q60865, (Rat) Q5M9G3
Entrez Gene ID: (Human) 4076, (Mouse) 53872, (Rat) 362173
deadenylation-dependent decapping of nuclear-transcribed mRNA
nervous system development
synapse assembly
intracellular mRNA localization
negative regulation of translation
cell differentiation
stress granule assembly
negative regulation of translational initiation
generation of neurons
positive regulation of dendrite morphogenesis
synapse organization
positive regulation of dendritic spine morphogenesis
positive regulation of stress granule assembly
regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA
membraneless organelle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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