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Proteintech
CBLB Monoclonal Antibody (2D3A2)
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Product Details
66353-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG3
Class
Monoclonal
Type
Antibody
Clone
2D3A2
Immunogen
CBLB Fusion Protein Ag18757 (1-352 aa encoded by BC032851)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MANSMNGRN PGGRGGNPRK GRILGIIDAI QDAVGPPKQA AADRRTVEKT WKLMDKVVRL CQNPKLQLKN SPPYILDILP DTYQHLRLIL SKYDDNQKLA QLSENEYFKI YIDSLMKKSK RAIRLFKEGK ERMYEEQSQD RRNLTKLSLI FSHMLAEIKA IFPNGQFQGD NFRITKADAA EFWRKFFGDK TIVPWKVFRQ CLHEVHQISS GLEAMALKST IDLTCNDYIS VFEFDIFTRL FQPWGSILRN WNFLAVTHPG YMAFLTYDEV KARLQKYSTK PGSYIFRLSC TRLGQWAIGY VTGDGNILQT IPHNKPLFQA LIDGSREGFY LYPDGRSYNP DLTGLCEPTP HDH (1-352 aa encoded by BC032851)
Target Information
This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the nucleus in testis and several other cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cas-Br-M (murine) ecotropic retroviral transforming sequence b; Cas-Br-M (murine) ectropic retroviral transforming sequence b; Casitas B-lineage lymphoma b; Casitas B-lineage lymphoma proto-oncogene b; Cbl proto-oncogene B, E3 ubiquitin protein ligase; Cbl proto-oncogene, E3 ubiquitin protein ligase B; E3 ubiquitin-protein ligase CBL-B; RING finger protein 56; RING-type E3 ubiquitin transferase CBL-B; SH3-binding protein CBL-B; Signal transduction protein CBL-B; unnamed protein product
Gene Aliases: ADMIO3; AI429560; AI851073; Cbl-b; CBLB; Nbla00127; RNF56
UniProt ID: (Human) Q13191, (Rat) Q8K4S7, (Mouse) Q3TTA7
Entrez Gene ID: (Human) 868, (Pig) 100621690, (Rat) 171136, (Mouse) 208650
phosphotyrosine binding
ubiquitin-protein transferase activity
calcium ion binding
protein binding
zinc ion binding
transferase activity
receptor tyrosine kinase binding
metal ion binding
ubiquitin protein ligase activity
signal transducer activity
ligase activity
protein kinase binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
damaged DNA-binding protein
ligase
metabolite interconversion enzyme
positive regulation of T cell anergy
T cell anergy
NLS-bearing protein import into nucleus
immune response
signal transduction
cell surface receptor signaling pathway
protein ubiquitination
regulation of signaling
regulation of cell adhesion
protein catabolic process
positive regulation of protein ubiquitination
intracellular signal transduction
CD4-positive, alpha-beta T cell proliferation
negative regulation of epidermal growth factor receptor signaling pathway
T cell activation
positive regulation of protein catabolic process
T cell receptor signaling pathway
negative regulation of T cell receptor signaling pathway
regulation of postsynaptic neurotransmitter receptor internalization
regulation protein catabolic process at postsynapse
negative regulation of CD4-positive, alpha-beta T cell proliferation
regulation of platelet-derived growth factor receptor-alpha signaling pathway
response to gravity
response to hormone
negative regulation of alpha-beta T cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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