Search
Proteintech
Calbindin-D28k Monoclonal Antibody (1F8B9)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
66394-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1F8B9
Immunogen
Calbindin-D28k Fusion Protein Ag5861 (109-262 aa encoded by BC006478)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KYDTDHSGF IETEELKNFL KDLLEKANKT VDDTKLAEYT DLMLKLFDSN NDGKLELTEM ARLLPVQENF LLKFQGIKMC GKEFNKAFEL YDQDGNGYID ENELDALLKD LCEKNKQDLD INNITTYKKN IMALSDGGKL YRTDLALILC AGDN (109-262 aa encoded by B C006478)
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin 27; Calbindin D28; calbindin-28K; calbindin-D (28k); calbindin-D28k; CalbindinD28K; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; retrovirus-like H primer binding sequence protein; RTVL-H protein; Spot 35 protein; unnamed protein product; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: Brain-2; CAB27; CaBP28K; CALB; Calb-1; CALB1; CB; D-28K
UniProt ID: (Human) P05937, (Rat) P07171, (Mouse) P12658
Entrez Gene ID: (Human) 793, (Pig) 100153645, (Rat) 83839, (Mouse) 12307
learning or memory
short-term memory
long-term memory
locomotory behavior
retina layer formation
response to auditory stimulus
metanephric part of ureteric bud development
regulation of synaptic plasticity
calcium ion homeostasis
retina development in camera-type eye
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
cochlea development
regulation of presynaptic cytosolic calcium ion concentration
regulation of postsynaptic cytosolic calcium ion concentration
vitamin D metabolic process
regulation of cytosolic calcium ion concentration
cellular response to organic substance
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support