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Proteintech
Heavy chain of IgG4 Monoclonal Antibody (1A1A2)
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FIGURE: 1 / 9
Heavy chain of IgG4 Antibody (66408-1-IG) in IHC (P)
Immunohistochemical analysis of paraffin-embedded Human tonsillitis tissue slide using (Product # 66408-1-Ig) Human IgG4 antibody at dilution of 1:5,000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
66408-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A1A2
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody detects the heavy chain of human IgG4. The immunogen of this antibody is the specific domain "NKGLPSSIEK" of IGHG4.
Target Information
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Immunoglobulin G; ImmunoglobulinG; ImmunoglobulinG4
Entrez Gene ID: (Human) 3503
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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