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Proteintech
PEBP1 Monoclonal Antibody (2D4D11)
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Product Details
66438-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2D4D11
Immunogen
PEBP1 Fusion Protein Ag0864 (83-187 aa encoded by BC008714)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EWHHFLVVN MKGNDISSGT VLSDYVGSGP PKGTGLHRYV WLVYEQDRPL KCDEPILSNR SGDHRGKFKV ASFRKKYELR APVAGTCYQA EWDDYVPKLY EQLSGK (83-187 aa encoded by BC008714)
Target Information
PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 23 kDa morphine-binding protein; epididymis luminal protein 210; epididymis secretory protein Li 34; epididymis secretory protein Li 96; HCNPpp; hippocampal cholinergic neurostimulating peptide; KIAA0299; LDGF; MDGF; MOCA; Neuropolypeptide h3; P23K; PEBP-1; Phosphatidylethanolamine-binding protein 1; PPBP; prostatic binding protein; Prostatic-binding protein; Raf kinase inhibitor protein; Raf kinase inhibitory protein; Raf-1 inhibitor protein; Raf-1 kinase inhibitor protein; RKIP; unnamed protein product
Gene Aliases: HCNP; HCNPpp; HEL-210; HEL-S-34; HEL-S-96; PBP; Pbp1; Pbpr; PEBP; PEBP-1; PEBP1; RKIP
UniProt ID: (Human) P30086, (Rat) P31044, (Mouse) P70296
Entrez Gene ID: (Human) 5037, (Rat) 29542, (Mouse) 23980
nucleotide binding
RNA binding
serine-type endopeptidase inhibitor activity
protein binding
ATP binding
lipid binding
phosphatidylethanolamine binding
enzyme binding
protein kinase binding
peptidase inhibitor activity
receptor binding
kinase binding
poly(A) RNA binding
mitogen-activated protein kinase binding
protease inhibitor
negative regulation of MAPK cascade
MAPK cascade
regulation of neurotransmitter levels
negative regulation of protein phosphorylation
regulation of the force of heart contraction
response to oxidative stress
spermatid development
brain development
aging
response to heat
response to wounding
response to toxic substance
response to organic substance
response to organonitrogen compound
negative regulation of endopeptidase activity
response to organic cyclic compound
response to activity
response to drug
eating behavior
positive regulation of cAMP-mediated signaling
response to ethanol
positive regulation of mitotic nuclear division
sperm capacitation
response to corticosterone
response to cAMP
response to calcium ion
response to electrical stimulus
positive regulation of acetylcholine metabolic process
negative regulation of peptidase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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