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Immunogen sequence: MVAPGLVLG LVLPLILWAD RSAGIGFRFA SYINNDMVLQ KEPAGAVIWG FGTPGATVTV TLRQGQETIM KKVTSVKAHS DTWMVVLDPM KPGGPFEVMA QQTLEKINFT LRVHDVLFGD VWLCSGQSNM QMTVLQIFNA TRELSNTAAY QSVRILSVSP IQAEQELEDL VAVDLQWSKP TSENLGHGYF KYMSAVCWLF GRHLYDTLQY PIGLIASSWG GTPIEAWSSG RSLKACGVPK QGSIPYDSVT GPSKHSVLWN AMIHPLCNMT LKGVVWYQGE SNINYNTDLY NCTFPALIED WRETFHRGSQ GQTERFFPFG LVQLSSDLSK KSSDDGFPQI RWHQTADFGY V (1-350 aa encoded by BC068450)
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: clone 165; cytosolic sialic acid 9-O-acetylesterase homolog; H-Lse; Sialate O-acetylesterase; Sialic acid-specific 9-O-acetylesterase; sialic acid-specific acetylesterase II; yolk sac gene 2; Yolk sac protein 2
Gene Aliases: AIS6; CSE-C; CSEC; LSE; RGD1310431; SIAE; YSG2
UniProt ID: (Human) Q9HAT2, (Mouse) P70665
Entrez Gene ID: (Human) 54414, (Pig) 100521812, (Mouse) 22619, (Rat) 363045
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