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Proteintech
MFF Monoclonal Antibody (1G4B12)
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Product Details
66527-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1G4B12
Immunogen
MFF Fusion Protein Ag9990 (1-238 aa encoded by BC000797)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes the endogenous MFF protein around 26-29 kDa and 35-38 kDa.
Immunogen sequence: MAEISRIQY EMEYTEGISQ RMRVPEKLKV APPNADLEQG FQEGVPNASV IMQVPERIVV AGNNEDVSFS RPADLDLIQS TPFKPLALKT PPRVLTLSER PLDFLDLERP PTTPQNEEIR AVGRLKRERS MSENAVRQNG QLVRNDSLPV LRGGSAAATS NPHHDNVRYG ISNIDTTIEG TSDDLTVVDA ASLRRQIIKL NRRLQLLEEE NKERAKREMV MYSITVAFWL LNSWLWFRR (1-238 aa encoded by BC000797 )
Target Information
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Mitochondrial fission factor; unnamed protein product
Gene Aliases: 5230400G24Rik; AD030; AD033; AI314724; C2orf33; EMPF2; GL004; MFF; RGD1310230
UniProt ID: (Human) Q9GZY8, (Rat) Q4KM98, (Mouse) Q6PCP5
Entrez Gene ID: (Pig) 100513442, (Human) 56947, (Rat) 301563, (Mouse) 75734
mitochondrial fission
release of cytochrome c from mitochondria
protein targeting to mitochondrion
mitochondrial fusion
regulation of mitochondrion organization
peroxisome fission
mitochondrial fragmentation involved in apoptotic process
protein homooligomerization
mitochondrion morphogenesis
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
positive regulation of protein targeting to membrane
regulation of peroxisome organization
mitochondrion organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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