Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
TBR1 Monoclonal Antibody (5C3A5)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
66564-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5C3A5
Immunogen
TBR1 Fusion Protein Ag15262 (1-196 aa encoded by BC104844)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQLEHCLSP SIMLSKKFLN VSSSYPHSGG SELVLHDHPI ISTTDNLERS SPLKKITRGM TNQSDTDNFP DSKDSPGDVQ RSKLSPVLDG VSELRHSFDG SAADRYLLSQ SSQPQSAATA PSAMFPYPGQ HGPAHPAFSI GSPSRYMAHH PVITNGAYNS LLSNSSPQGY PTAGYPYPQQ YGHSYQGAPF YQFSSTQ (1-196 aa encoded by BC104844)
Target Information
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: T-box brain gene 1; T-box brain protein 1; T-box, brain 1; T-box, brain, 1; T-box, brain, 1-like; T-brain-1; TBR-1; TES-56
Gene Aliases: TBR-1; TBR1; TES-56
UniProt ID: (Human) Q16650, (Mouse) Q64336
Entrez Gene ID: (Human) 10716, (Pig) 100154282, (Mouse) 21375, (Rat) 680427
conditioned taste aversion
transcription, DNA-templated
brain development
specification of organ identity
amygdala development
commitment of neuronal cell to specific neuron type in forebrain
hindbrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of axon guidance
regulation of transcription, DNA-templated
regulation of gene expression
regulation of neuron projection development
neuron differentiation
axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support