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Proteintech

WNT2 Monoclonal Antibody (3H7B10)

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View all (15) WNT2 antibodies

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WNT2 Monoclonal Antibody (3H7B10)

Product Details

66656-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:5,000-1:20,000
View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

1:100
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3H7B10

Immunogen

WNT2 Fusion Protein Ag25185 (1-360 aa encoded by BC029854)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

150 µg

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MNAPLGGIW LWLPLLLTWL TPEVNSSWWY MRATGGSSRV MCDNVPGLVS SQRQLCHRHP DVMRAISQGV AEWTAECQHQ FRQHRWNCNT LDRDHSLFGR VLLRSSRESA FVYAISSAGV VFAITRACSQ GEVKSCSCDP KKMGSAKDSK GIFDWGGCSD NIDYGIKFAR AFVDAKERKG KDARALMNLH NNRAGRKAVK RFLKQECKCH GVSGSCTLRT CWLAMADFRK TGDYLWRKYN GAIQVVMNQD GTGFTVANER FKKPTKNDLV YFENSPDYCI RDREAGSLGT AGRVCNLTSR GMDSCEVMCC GRGYDTSHVT RMTKCGCKFH WCCAVRCQDC LEALDVHTCK APKNADWTTA T (1-360 aa encoded by BC029854)

Target Information

WNT2 is a ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: epididymis secretory sperm binding protein; Int-1-like protein 1; INT-1-related protein; INT1L 1; IRP; IRP protein; Protein Wnt-2; secreted growth factor; unnamed protein product; wingless-related MMTV integration site 2; wingless-type MMTV integration site 2; wingless-type MMTV integration site family member 2; WNT 2

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Gene Aliases: 2610510E18Rik; INT1L1; IRP; Mirp; Wnt; Wnt-2; WNT2; Wnt2a

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UniProt ID: (Human) P09544, (Mouse) P21552

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Entrez Gene ID: (Human) 7472, (Mouse) 22413, (Rat) 114487

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Function(s)
receptor binding frizzled binding cytokine activity protein binding receptor agonist activity molecular_function intercellular signal molecule
Process(es)
positive regulation of mesenchymal cell proliferation lens development in camera-type eye cell-cell signaling positive regulation of cell proliferation mesenchymal cell proliferation Wnt signaling pathway neurogenesis neuron differentiation cell proliferation in midbrain cell fate commitment positive regulation of transcription from RNA polymerase II promoter positive regulation of fibroblast proliferation animal organ development system development epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of neurogenesis atrial cardiac muscle tissue morphogenesis cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation canonical Wnt signaling pathway cardiac epithelial to mesenchymal transition lung induction positive regulation of epithelial cell proliferation involved in lung morphogenesis epithelial cell proliferation involved in lung morphogenesis labyrinthine layer blood vessel development iris morphogenesis mammary gland epithelium development cellular response to retinoic acid cellular response to transforming growth factor beta stimulus midbrain dopaminergic neuron differentiation positive regulation of endothelial cell proliferation multicellular organism development positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of canonical Wnt signaling pathway lung development
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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