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Proteintech
XIAP Monoclonal Antibody (2A1A12)
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Product Details
66800-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2A1A12
Immunogen
XIAP Fusion Protein Ag18088 (1-497 aa encoded by BC032729)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
75 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTFNSFEGS KTCVPADINK EEEFVEEFNR LKTFANFPSG SPVSASTLAR AGFLYTGEGD TVRCFSCHAA VDRWQYGDSA VGRHRKVSPN CRFINGFYLE NSATQSTNSG IQNGQYKVEN YLGSRDHFAL DRPSETHADY LLRTGQVVDI SDTIYPRNPA MYSEEARLKS FQNWPDYAHL TPRELASAGL YYTGIGDQVQ CFCCGGKLKN WEPCDRAWSE HRRHFPNCFF VLGRNLNIRS ESDAVSSDRN FPNSTNLPRN PSMADYEARI FTFGTWIYSV NKEQLARAGF YALGEGDKVK CFHCGGGLTD WKPSEDPWEQ HAKWYPGCKY LLEQKGQEYI NNIHLTHSLE ECLVRTTEKT PSLTRRIDDT IFQNPMVQEA IRMGFSFKDI KKIMEEKIQI SGSNYKSLEV LVADLVNAQK DSMQDESSQT SLQKEISTEE QLRRLQEEKL CKICMDRNIA IVFVPCGHLV TCKQCAEAVD KCPMCYTVIT FKQKIFMS (1-497 aa encoded by BC032729)
Target Information
ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: apoptosis inhibitor protein 3; baculoviral IAP repeat-containing 4; Baculoviral IAP repeat-containing protein 4; BIR4; E3 ubiquitin-protein ligase XIAP; HILP; IAP homolog A; IAP-3; IAP-like protein; IAP-like protein 1; ILP; Inhibitor of apoptosis protein 3; RIAP-3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; unnamed protein product; X-linked IAP; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
Gene Aliases: 1110015C02Rik; Aipa; API3; BIRC4; hIAP-3; hIAP3; IAP-3; IAP3; ILP-1; ILP1; MIHA; riap3; XIAP; XLP2
UniProt ID: (Human) P98170, (Rat) Q9R0I6, (Mouse) Q60989
Entrez Gene ID: (Human) 331, (Rat) 63879, (Mouse) 11798
ubiquitin-protein transferase activity
cysteine-type endopeptidase inhibitor activity
protein binding
zinc ion binding
transferase activity
peptidase inhibitor activity
identical protein binding
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
metal ion binding
ubiquitin protein ligase activity
protein serine/threonine kinase binding
protease binding
ligase activity
scaffold protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protease inhibitor
ubiquitin-dependent protein catabolic process
apoptotic process
cellular response to DNA damage stimulus
I-kappaB kinase/NF-kappaB signaling
negative regulation of tumor necrosis factor-mediated signaling pathway
Wnt signaling pathway
regulation of BMP signaling pathway
positive regulation of protein ubiquitination
negative regulation of type I interferon production
positive regulation of type I interferon production
response to lipopolysaccharide
p38MAPK cascade
defense response to bacterium
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of I-kappaB kinase/NF-kappaB signaling
regulation of innate immune response
positive regulation of JNK cascade
regulation of inflammatory response
neuron apoptotic process
regulation of cell cycle
copper ion homeostasis
regulation of apoptosis involved in tissue homeostasis
regulation of nucleotide-binding oligomerization domain containing signaling pathway
nucleotide-binding oligomerization domain containing 1 signaling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway
protein K63-linked ubiquitination
positive regulation of canonical Wnt signaling pathway
protein linear polyubiquitination
execution phase of apoptosis
positive regulation of protein linear polyubiquitination
protein ubiquitination
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of neuron apoptotic process
mitotic spindle assembly
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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