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          • Primary Antibodies ›
          • NEU1 Antibodies

          Proteintech

          NEU1 Monoclonal Antibody (1F6D1)

          5 References
          View all (25) NEU1 antibodies

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          Cite NEU1 Monoclonal Antibody (1F6D1)

          Additional Information:
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          • Antibody Testing Data (3)
          NEU1 Antibody in Immunocytochemistry (ICC/IF)
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          NEU1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          NEU1 Antibody (67032-1-IG) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed U-251 cells using 67032-1-Ig (NEU1 antibody), at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          NEU1 Antibody in Immunocytochemistry (ICC/IF)
          NEU1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NEU1 Antibody in Western Blot (WB)

          Product Details

          67032-1-IG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:3,000
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:300
          -

          Immunocytochemistry (ICC/IF)

          1:200
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Pig, Rat

          Published species

          Human, Mouse

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1F6D1

          Immunogen

          NEU1 Fusion Protein Ag27945

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • CoraLite Plus 488
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1000 µg/mL

          Amount

          150 µg

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Aliquoting is unnecessary for -20°C storage.

          Target Information

          NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Acetylneuraminyl hydrolase; EC 3.2.1.18; exo-alpha-sialidase; FLJ93471; G9 sialidase; hydrolytic enzyme of the sialidase family; Lysosomal sialidase; N-acetyl-alpha-neuraminidase 1; NEU1; sialidase 1 (lysosomal sialidase); Sialidase-1; unnamed protein product

          View more View less

          Gene Aliases: NANH; NEU; NEU1; SIAL1

          View more View less

          UniProt ID: (Pig) A5PF10, (Human) Q99519

          View more View less

          Entrez Gene ID: (Pig) 100124381, (Human) 4758, (Rat) 24591

          View more View less

          Function(s)
          exo-alpha-sialidase activity protein binding hydrolase activity hydrolase activity, acting on glycosyl bonds alpha-sialidase activity exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity hydrolase
          Process(es)
          lipid metabolic process ganglioside catabolic process oligosaccharide catabolic process lipid catabolic process positive regulation of neuron projection development regulation of myoblast proliferation
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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