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Proteintech
USF1 Monoclonal Antibody (1C8F1)
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Product Details
67114-1-IG
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1C8F1
Immunogen
USF1 Fusion Protein Ag17785
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHb11; Class B basic helix-loop-helix protein 11; Major late transcription factor 1; unnamed protein product; Upstream stimulatory factor 1; usf1-bd
Gene Aliases: BHLHB11; FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; USF; USF1
UniProt ID: (Human) P22415, (Mouse) Q61069
Entrez Gene ID: (Human) 7391, (Rat) 83586, (Mouse) 22278
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
enzyme binding
protein kinase binding
identical protein binding
protein homodimerization activity
histone deacetylase binding
bHLH transcription factor binding
sequence-specific DNA binding
macromolecular complex binding
protein heterodimerization activity
protein dimerization activity
sequence-specific double-stranded DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
regulation of transcription from RNA polymerase II promoter by glucose
positive regulation of transcription from RNA polymerase II promoter by glucose
response to hypoxia
glucose metabolic process
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
response to UV
glucose mediated signaling pathway
late viral transcription
cellular response to insulin stimulus
glucose homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
carbon catabolite regulation of transcription
negative regulation of fibrinolysis
lipid homeostasis
cellular response to glucose stimulus
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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