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Proteintech
Cytohesin 2 Monoclonal Antibody (3A7A1)
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Product Details
67185-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3A7A1
Immunogen
CYTH2 Fusion Protein Ag21279
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ARF exchange factor; ARF nucleotide binding site opener; ARF nucleotide-binding site opener; CLM2; CTC-273B12.8; cytohesin family member; Cytohesin-2; hypothetical; similar to yeast Sec7p, Swiss-Prot Accession Number P11075; mSec7-2; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and coiled-coil domains 2; pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2); Protein ARNO; SEC7 homolog B; unnamed protein product
Gene Aliases: ARNO; CLM2; CTS18; CTS18.1; CYTH2; cytohesin-2; PSCD2; PSCD2L; Sec7; Sec7B; SEC7L; Sec7p-L; Sec7p-like
UniProt ID: (Human) Q99418, (Rat) P63035, (Mouse) P63034
Entrez Gene ID: (Human) 9266, (Rat) 116692, (Mouse) 19158
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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