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Proteintech
SETD1A Monoclonal Antibody (1C2G12)
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Product Details
67936-1-IG150UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1C2G12
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Histone-lysine N-methyltransferase SETD1A; hSET1A; Lysine N-methyltransferase 2F; non-selective cation channel 1; SET domain-containing protein 1A; Set1/Ash2 histone methyltransferase complex subunit SET1
Gene Aliases: BC010250; EPEDD; EPEO2; KIAA0339; KMT2F; mKIAA0339; mNSC1; NEDSID; Nsccn1; RGD1311624; SET1; SET1A; SETD1A
UniProt ID: (Human) O15047, (Mouse) E9PYH6
Entrez Gene ID: (Human) 9739, (Mouse) 233904, (Rat) 309001
nucleic acid binding
RNA binding
protein binding
beta-catenin binding
methyltransferase activity
transferase activity
histone methyltransferase activity (H3-K4 specific)
RNA polymerase II sequence-specific DNA binding transcription factor binding
histone H3 methyltransferase activity
histone H3K4 monomethyltransferase activity
histone H3K4 trimethyltransferase activity
histone-lysine N-methyltransferase activity
euchromatin binding
histone modifying enzyme
chromatin organization
chromatin remodeling
cellular response to DNA damage stimulus
brain development
methylation
regulation of hematopoietic stem cell differentiation
regulation of chromatin organization
stem cell population maintenance
chromatin-mediated maintenance of transcription
histone H3-K4 methylation
positive regulation of neural precursor cell proliferation
positive regulation of stem cell proliferation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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