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Proteintech
ACOX1 Monoclonal Antibody (3E12E10)
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Product Details
68017-1-IG150UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3E12E10
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACO; acyl-CoA oxidase 1, palmitoyl; acyl-CoA oxidase, straight-chain; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; Palmitoyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 1; Peroxisomal fatty acyl-CoA oxidase; peroxisomal fatty acyl-coenzyme A oxidase; peroxisomal straight-chain Acyl-CoA oxidase; SCOX; Straight-chain acyl-CoA oxidase; unnamed protein product
Gene Aliases: ACOX; ACOX1; AOX; D130055E20Rik; MITCH; PALMCOX; Paox; RATACOA1; SCOX
UniProt ID: (Human) Q15067, (Rat) P07872, (Mouse) Q9R0H0
Entrez Gene ID: (Human) 51, (Rat) 50681, (Mouse) 11430
acyl-CoA oxidase activity
fatty acid binding
protein binding
palmitoyl-CoA oxidase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
PDZ domain binding
protein homodimerization activity
flavin adenine dinucleotide binding
FAD binding
acyl-CoA dehydrogenase activity
receptor binding
protein N-terminus binding
oxidoreductase
very long-chain fatty acid metabolic process
generation of precursor metabolites and energy
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
unsaturated fatty acid biosynthetic process
prostaglandin metabolic process
spermatogenesis
fatty acid catabolic process
peroxisome fission
fatty acid oxidation
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
cholesterol homeostasis
long-chain fatty acid biosynthetic process
hydrogen peroxide biosynthetic process
lipid homeostasis
very long-chain fatty acid beta-oxidation
fatty acid derivative biosynthetic process
positive regulation of cholesterol homeostasis
metabolic process
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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