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Proteintech
Histone H2B Monoclonal Antibody (1E12G3)
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Product Details
68393-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat,
Zebrafish
Published species
Chicken,
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1E12G3
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
150 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Acetyl-Histone H2; H2B; H2B 291A; H2B 291B; H2b 613; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B I; H2B II; H2B III; H2B IV; H2B K; H2B type 12; H2B VI; h2B-143; h2B-221; H2B-clustered histone 17; H2B-clustered histone 18; H2B-clustered histone 21; H2B-clustered histone 26; H2B-clustered histone 3; H2B-clustered histone 5; H2B-clustered histone 9; H2B.1 antibody; H2B.E variant histone 1; H2B.M histone; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/s; H2BK12ac; H2BK15ac; H2BK5ac; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIST1H2BB antibody; HIST1H3I; HIST2H2BE; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1 H2B family member a; histone cluster 1 H2B family member b; histone cluster 1 H2B family member c; histone cluster 1 H2B family member d; histone cluster 1 H2B family member g; histone cluster 1 H2B family member h; histone cluster 1 H2B family member i; histone cluster 1 H2B family member j; histone cluster 1 H2B family member k; histone cluster 1 H2B family member l; histone cluster 1 H2B family member m; histone cluster 1 H2B family member n; histone cluster 1 H2B family member o; histone cluster 1, H2B-VII-like 3 (similar to human histone cluster 1, class H2B, member N); histone cluster 1, H2ba; histone cluster 1, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bg; histone cluster 1, H2bh; histone cluster 1, H2bi; histone cluster 1, H2bj; histone cluster 1, H2bk; histone cluster 1, H2bl; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2 H2B family member e; histone cluster 2 H2B family member f; histone cluster 2, H2be; histone cluster 2, H2bf; histone cluster 3 H2B family member b; histone cluster 3, H2bb; histone family member; histone H2B; Histone H2B 1/2/3/4/6; Histone H2B 3; Histone H2B type 1-A; Histone H2B type 1-B; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-D; Histone H2B type 1-F/J/L; Histone H2B type 1-H; Histone H2B type 1-J; Histone H2B type 1-K; Histone H2B type 1-L; Histone H2B type 1-M; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-E1; Histone H2B type 2-F; Histone H2B type 2-K1; Histone H2B type 3-B; Histone H2B type F-M; Histone H2B type W-T; Histone H2B, testis; Histone H2B-GL105; Histone H2B.1; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.2; Histone H2B.a; Histone H2B.b; Histone H2B.c; Histone H2B.d; Histone H2B.e; Histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B.r; Histone H2B.s; MGC125414; MGC125415; MGC125416; MGC9388; novel histone H2B-like protein; RP1-193B12.10; testis-specific histone 2b; Testis-specific histone H2B; TSH2B.1; unnamed protein product
Gene Aliases: 2610022J01Rik; AV127319; bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; fj05g08; GL105; H2B; H2b-143; H2b-221; H2b-291b; H2b-613; H2b-f; H2B-GL105; H2B-I; H2B-II; H2B-III; H2B-IV; H2b-j; H2b-l; H2b-n; H2B-VI; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/j; H2B/k; H2B/l; H2B/n; H2B/r; H2B/S; H2Bb; H2BC1; H2BC10; H2BC11; H2BC12; H2BC13; H2BC14; H2BC15; H2BC17; H2BC18; H2BC21; H2BC26; H2BC3; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BC9; H2BE; H2BE1; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2BK; H2BK1; H2BM; H2BQ; H2BU1; H2BW1; H2BW2; HIRIP1; HIRIP2; HIST1H2B7L3; HIST1H2BA; HIST1H2BB; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BH; HIST1H2BI; HIST1H2BJ; HIST1H2BK; HIST1H2BL; HIST1H2BM; HIST1H2BN; HIST1H2BO; HIST2H2BE; HIST2H2BF; hist2h2l; HIST3H2BB; hTSH2B; R74621; si:dkey-108k21.9; STBP; T25626; TH2B; TH2B-175; TSH2B; TSH2B.1; wu:fj05g08; zgc:73093
UniProt ID: (Human) Q96A08, (Human) P62807, (Human) P06899, (Human) O60814, (Human) Q99880, (Human) Q99879, (Human) Q99877, (Human) P23527, (Human) Q5QNW6, (Human) Q16778, (Human) Q8N257, (Human) P33778, (Human) Q93079, (Human) A0A2R8Y619, (Human) Q7Z2G1, (Human) P0C1H6, (Chicken) P0C1H3, (Rat) Q00729, (Mouse) P70696, (Mouse) Q64475, (Mouse) Q6ZWY9, (Mouse) Q64478, (Mouse) P10853, (Mouse) Q8CGP1, (Mouse) P10854, (Mouse) Q64524, (Zebrafish) Q6PC60
Entrez Gene ID: (Human) 255626, (Human) 8346, (Human) 8970, (Human) 85236, (Human) 8340, (Human) 8342, (Human) 8341, (Human) 8348, (Human) 440689, (Human) 8349, (Human) 128312, (Human) 3018, (Human) 8347, (Human) 3017, (Human) 8339, (Human) 8345, (Human) 114483833, (Human) 158983, (Human) 286436, (Chicken) 100858607, (Rat) 24829, (Mouse) 319177, (Mouse) 319178, (Mouse) 68024, (Rat) 361247, (Mouse) 319181, (Mouse) 319182, (Mouse) 319183, (Mouse) 319184, (Rat) 680312, (Mouse) 319186, (Rat) 291157, (Mouse) 319190, (Rat) 691488, (Zebrafish) 100329290, (Zebrafish) 100329560, (Zebrafish) 100334559, (Zebrafish) 100334869, (Human) 102724334, (Chicken) 426037, (Zebrafish) 100333496, (Zebrafish) 386920
chromatin organization
nucleosome assembly
nucleosome disassembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
innate immune response in mucosa
antibacterial humoral response
defense response to bacterium
defense response to Gram-positive bacterium
antimicrobial humoral immune response mediated by antimicrobial peptide
negative regulation of tumor necrosis factor-mediated signaling pathway
killing of cells of other organism
defense response to Gram-negative bacterium
protein localization to CENP-A containing chromatin
mitotic chromosome condensation
spermatogenesis, exchange of chromosomal proteins
positive regulation of binding
cellular response to acid chemical
biological_process
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