IL-1 beta Recombinant Superclonal™ Antibody (17HCLC)

cytokine activity interleukin-1 receptor binding integrin binding protein binding protein domain specific binding receptor agonist activity receptor binding interleukin superfamily

fever generation positive regulation of cytokine production positive regulation of T cell mediated immunity apoptotic process inflammatory response immune response signal transduction JNK cascade cell-cell signaling embryo implantation positive regulation of cell proliferation negative regulation of cell proliferation response to carbohydrate vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production positive regulation of gene expression positive regulation of platelet-derived growth factor receptor signaling pathway positive regulation of epithelial to mesenchymal transition positive regulation of macrophage derived foam cell differentiation negative regulation of glucose transport smooth muscle adaptation cytokine-mediated signaling pathway hyaluronan biosynthetic process positive regulation of cell migration neutrophil chemotaxis positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of prostaglandin biosynthetic process positive regulation of fever generation positive regulation of prostaglandin secretion response to lipopolysaccharide positive regulation of chemokine production positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of interferon-gamma production positive regulation of interleukin-2 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of immature T cell proliferation in thymus response to ATP positive regulation of heterotypic cell-cell adhesion ectopic germ cell programmed cell death positive regulation of T cell proliferation regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of nitric oxide biosynthetic process positive regulation of angiogenesis negative regulation of lipid metabolic process positive regulation of mitotic nuclear division positive regulation of transcription, DNA-templated positive regulation of complement activation positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade negative regulation of insulin receptor signaling pathway positive regulation of protein export from nucleus astrocyte activation regulation of defense response to virus by host positive regulation of inflammatory response regulation of neurogenesis negative regulation of neurogenesis regulation of insulin secretion negative regulation of synaptic transmission defense response to Gram-positive bacterium leukocyte migration negative regulation of lipid catabolic process positive regulation of lipid catabolic process regulation of nitric-oxide synthase activity positive regulation of membrane protein ectodomain proteolysis positive regulation of cell division positive regulation of protein kinase B signaling positive regulation of glial cell proliferation positive regulation of cell adhesion molecule production negative regulation of adiponectin secretion regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade monocyte aggregation interleukin-1-mediated signaling pathway response to interleukin-1 cellular response to lipopolysaccharide cellular response to mechanical stimulus cellular response to xenobiotic stimulus positive regulation of monocyte chemotactic protein-1 production extrinsic apoptotic signaling pathway in absence of ligand cellular response to interleukin-17 positive regulation of neuroinflammatory response positive regulation of p38MAPK cascade positive regulation of NIK/NF-kappaB signaling positive regulation of RNA biosynthetic process regulation of establishment of endothelial barrier regulation of secretion by cell negative regulation of gap junction assembly positive regulation of occluding junction disassembly positive regulation of T-helper 1 cell cytokine production negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of transcription from RNA polymerase II promoter MAPK cascade activation of MAPK activity positive regulation of protein phosphorylation positive regulation of cytosolic calcium ion concentration aging memory negative regulation of gene expression positive regulation of cell death negative regulation of glutamate secretion sequestering of triglyceride lipopolysaccharide-mediated signaling pathway interleukin-1 beta production positive regulation of stress-activated MAPK cascade social behavior positive regulation of myosin light chain kinase activity cellular response to drug positive regulation of NF-kappaB import into nucleus positive regulation of apoptotic process negative regulation of MAP kinase activity protein kinase B signaling positive regulation of JUN kinase activity positive regulation of chemokine biosynthetic process positive regulation of interleukin-2 biosynthetic process positive regulation of interleukin-6 biosynthetic process negative regulation of neuron differentiation positive regulation of glial cell differentiation positive regulation of astrocyte differentiation positive regulation of phagocytosis positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of calcidiol 1-monooxygenase activity cellular response to organic substance cellular response to organic cyclic compound positive regulation of neutrophil chemotaxis negative regulation of branching morphogenesis of a nerve negative regulation of neural precursor cell proliferation