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Invitrogen
MCHR1 Polyclonal Antibody
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FIGURE: 1 / 4
MCHR1 Antibody (720294) in ICC/IF
HEK 293 cells were grown on poly-L-lysine-coated coverslips overnight. Cells were then transiently transfected with Melanin concentrating hormone receptor 1/MCHR1. After 24 h, cells were fixed with 4% paraformaldehyde and 0.2% picric acid in phosphate buffer (pH 6.9) for 30 min at room temperature and washed several times with phosphate buffer. Specimens were permeabilized with ice-cold methanol and then incubated with Anti-Melanin concentrating hormone receptor 1/MCHR1 RAbbit Polyclonal Antibody (Product # 720294 at a concentration of 2 µ... View More
Product Details
720294
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide corresponding to Human MCHR1 (aa 401-422)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.1% BSA, 30% glycerol
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey, Mouse and Rabbit.
Target Information
MCHR1 is a member of the G protein-coupled receptor family 1. It is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor 24; G-protein coupled receptor; G-protein coupled receptor 24; GPCR24; GPR24; MCH 1 receptor; MCH receptor 1; MCH-1R; MCH1; MCH1R; Melanin-concentrating hormone receptor 1; SLC-1; Somatostatin receptor-like protein; unnamed protein product
Gene Aliases: GPR24; MCH-1R; MCH1R; MCHR1; SLC-1; SLC1
UniProt ID: (Human) Q99705
Entrez Gene ID: (Human) 2847
generation of precursor metabolites and energy
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
feeding behavior
positive regulation of calcium ion transport
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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