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Kv1.5 K+ Channel Monoclonal Antibody (K7/45)
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Product Details
75-011
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K7/45
Immunogen
Fusion protein amino acids 542-602 (cytoplasmic C-terminus) of rat Kv1.5 (accession number P19024) produced recombinantly in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
In neurons voltage-dependent potassium channels are key determinants of the resting membrane potential and of membrane excitability, conditioning the frequency, and shape of action potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac potassium channel; HPCN1; insulinoma and islet potassium channel; KV1-5; MGC117058; MGC117059; Potassium (K+) channel protein alpha 5; potassium channel 1; potassium channel, voltage gated shaker related subfamily A, member 5; potassium voltage gated channel, shaker related subfamily, member 5; Potassium voltage-gated channel subfamily A member 5; potassium voltage-gated channel, shaker-related subfamily, member 5; RCK7; RK4; Voltage-gated potassium channel HK2; voltage-gated potassium channel protein Kv1.5; Voltage-gated potassium channel subunit Kv1.5
Gene Aliases: ATFB7; HCK1; HK2; HPCN1; KCNA5; Kv1; KV1.5; PCN1
UniProt ID: (Human) P22460, (Rat) P19024, (Mouse) Q61762
Entrez Gene ID: (Human) 3741, (Rat) 25470, (Mouse) 16493
receptor binding
ion channel activity
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
potassium channel activity
protein binding
outward rectifier potassium channel activity
protein kinase binding
alpha-actinin binding
voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization
voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
voltage-gated potassium channel activity involved in SA node cell action potential repolarization
scaffold protein binding
potassium channel inhibitor activity
voltage-gated ion channel activity
voltage-gated ion channel
action potential
response to hypoxia
ion transport
potassium ion transport
Notch signaling pathway
response to mechanical stimulus
regulation of vasoconstriction
ion transmembrane transport
regulation of membrane potential
response to hydrogen peroxide
regulation of insulin secretion
protein oligomerization
protein homooligomerization
negative regulation of cytosolic calcium ion concentration
potassium ion homeostasis
transmembrane transport
response to hyperoxia
membrane hyperpolarization
regulation of atrial cardiac muscle cell membrane repolarization
potassium ion transmembrane transport
atrial cardiac muscle cell action potential
membrane repolarization during bundle of His cell action potential
membrane repolarization during SA node cell action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during atrial cardiac muscle cell action potential
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of myoblast proliferation
response to organic substance
regulation of potassium ion transport
negative regulation of potassium ion transport
potassium ion export
transport
regulation of ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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