Hamburger Menu Button
Thermo Fisher Scientific Logo
Iniciar sesión
¿No tiene una cuenta? Crear una cuenta
  • Productos
    • Consumibles de laboratorio
    • Equipos de laboratorio
    • Instrumentos de Laboratorio
    • Clínica y Diagnóstico
    • Cromatografía
    • Espectrometría de Masas
    • Cultivo Celular
    • Análisis Celular
    • Anticuerpos
    • Ver todas las categorías de producto
  • Aplicaciones
    • Cultivo celular y transfección
    • Citometría de flujo
    • Investigación sobre el cáncer
    • Cromatografía
    • Secuenciación
    • PCR
    • Soluciones para laboratorio
    • Diagnóstico de alergias
    • Ver todas las aplicaciones y técnicas
  • Servicios
    • Servicios Personalizados
    • Servicios de Capacitación
    • Informática para laboratorios de ámbito empresarial
    • Servicios financieros y de arrendamiento
    • Servicios 360° de CDMO y CRO
    • Servicios de CDMO
    • Servicios de CRO
    • Ver todos los servicios
  • Ayuda y Soporte
    • Crear una nueva cuenta
    • Cómo hacer el pedido
    • Póngase en contacto con nosotros
    • Cambio de ubicación
    • Ver toda la ayuda y soporte técnico
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • A quiénes brindamos nuestros servicios
    • Industria biotecnológica
    • Sector biofarmacéutico
    • CDMO
    • Diagnósticos de laboratorio
    • Ciencias aplicadas e industriales
  • Ofertas especiales
  • Contáctenos
  • Orden Rápida
  • Documentos y certificados
Thermo Fisher Scientific Logo

Search

Buscar
Search button
          • Contáctenos
          • Orden Rápida
          • Iniciar sesión
            Iniciar sesión
            ¿No tiene una cuenta? Crear una cuenta
            • Cuenta
            • Pedidos
            • Productos y proyectos personalizados
          • Primary Antibodies ›
          • Pan-MAGUK Antibodies

          Antibodies Inc

          Pan-MAGUK Monoclonal Antibody (K28/86)

          View all (5) Pan-MAGUK antibodies

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support

          Cite Pan-MAGUK Monoclonal Antibody (K28/86)

          Additional Information:
          {{banner.description}}
          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
          • Antibody Testing Data (2)
          Pan-MAGUK Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          Pan-MAGUK Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

          {{ $ctrl.currentElement.advancedVerification.fullName }}
          {{ $ctrl.currentElement.advancedVerification.text }}

          Pan-MAGUK Antibody (75-029) in WB

          Immunoblot against crude C. elegans worm extracts and crude brain membranes from adult rat (RBM) probed with K28/86 TC supe. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

          {{$ctrl.videoDesc}}

          {{$ctrl.videoLongDesc}}

          Pan-MAGUK Antibody in Western Blot (WB)
          Pan-MAGUK Antibody in Western Blot (WB)
          Pan-MAGUK Monoclonal Antibody (K28/86)

          Product Details

          75-029

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Frozen) (IHC (F))

          Assay-dependent
          -

          Immunocytochemistry (ICC/IF)

          Assay-dependent
          -

          ELISA (ELISA)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat, Xenopus, Zebrafish

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          K28/86

          Immunogen

          Fusion protein amino acids 77-299 of human PSD-95/SAP90 produced recombinantly in E. Coli.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • FL490
          • FL550
          • FL594
          • FL650
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          TBS, pH 7.4

          Contains

          0.065% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Dry ice (international)

          Product Specific Information

          For maximum recovery of product, centrifuge the vial prior to removing the cap.

          Target Information

          Pan-MAGUK refers to the collective group of Membrane-Associated Guanylate Kinase (MAGUK) family proteins, which are scaffolding proteins involved in organizing signaling complexes at cellular membranes. These proteins play critical roles in synaptic signaling, cell adhesion, and maintaining the structure of tight junctions. Dysregulation of MAGUK proteins has been linked to various neurological disorders and cancers.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Channel-associated protein of synapse-110; channel-associated protein of synapses, 110kDa; Chapsyn-110; discs large homolog 1, scribble cell polarity complex component; discs large homolog 2; discs large homolog 3; discs large homolog 4; discs, large homolog 2, chapsyn-110; discs, large homolog 3; discs, large homolog 4; Disks large homolog 1; Disks large homolog 2; Disks large homolog 3; Disks large homolog 4; dJ1061C18.1.1; Drosophila discs-large tumor suppressor homologue (synapse associated protein); E-dlg/SAP97; Embryo-dlg/synapse-associated protein 97; hDlg; membrane associated guanylate kinase; MAGUK; Neuroendocrine-DLG; post-synaptic density protein 95; Postsynaptic density protein 93; Postsynaptic density protein 95; Postsynaptic density protein PSD-93; presynaptic protein SAP97; protein phosphatase 1, regulatory subunit 58; protein phosphatase 1, regulatory subunit 82; PSD-93; PSD-95; PSD-95 alpha 2b; PSD-95 beta; PSD-95/SAP90-related protein 1; SAP-102; SAP-90; SAP-97; SAP-97A; SAP102; SAP97A; Synapse-associated protein 102; Synapse-associated protein 90; Synapse-associated protein 97; Synapse-associated protein 97A; synapse-associated protein SAP90; synaptic density protein PSD-93; Tax interaction protein 15; unnamed protein product; XLMR

          View more View less

          Gene Aliases: A330103J02Rik; B130052P05Rik; B230218P12Rik; B330007M19Rik; chapsyn-110; DLG1; DLG2; DLG3; DLG4; DLGH1; Dlgh2; Dlgh3; Dlgh4; E-dlg/SAP97; fa66c08; fa66e02; fd02c12; fu95c12; Gm1197; hdlg; im:7138640; KIAA1232; mKIAA1232; mKIAA4187; MRD62; MRX; MRX90; NEDLG; PPP1R58; PPP1R82; PSD-93; PSD-95; PSD93; PSD95; SAP-90; SAP-97; SAP-97A; SAP102; SAP90; SAP90A; SAP97; si:ch211-276g21.1; wu:fa66c08; wu:fa66e02; wu:fc34d02; wu:fd02c12; wu:fu95c12; XLID90; XLMR; zgc:55810

          View more View less

          UniProt ID: (Human) Q12959, (Human) Q15700, (Human) Q92796, (Human) P78352, (Rat) Q62696, (Mouse) Q811D0, (Mouse) Q91XM9, (Rat) Q63622, (Rat) Q62936, (Mouse) P70175, (Rat) P31016, (Mouse) Q62108, (Zebrafish) Q5PYH6, (Zebrafish) Q5PYH7

          View more View less

          Entrez Gene ID: (Human) 1739, (Human) 1740, (Human) 1741, (Human) 1742, (Rat) 25252, (Mouse) 13383, (Mouse) 23859, (Rat) 64053, (Rat) 58948, (Mouse) 53310, (Rat) 29495, (Mouse) 13385, (Zebrafish) 114446, (Zebrafish) 497638, (Zebrafish) 564081, (Western clawed frog) 779559, (Zebrafish) 100000823

          View more View less

          Function(s)
          guanylate kinase activity phosphoprotein phosphatase activity protein binding cytoskeletal protein binding potassium channel regulator activity kinase binding protein kinase binding phosphatase binding ionotropic glutamate receptor binding ion channel binding cadherin binding binding, bridging L27 domain binding structural constituent of postsynaptic density ubiquitin protein ligase binding protein phosphatase binding PDZ domain binding protein binding, bridging beta-1 adrenergic receptor binding D1 dopamine receptor binding P2Y1 nucleotide receptor binding acetylcholine receptor binding macromolecular complex binding neuroligin family protein binding scaffold protein binding protein C-terminus binding mitogen-activated protein kinase kinase binding protein complex scaffold protein heterodimerization activity protein domain specific binding receptor binding protein complex binding glutamate receptor binding structural molecule activity neurexin family protein binding scaffold/adaptor protein
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter ureteric bud development branching involved in ureteric bud morphogenesis immunological synapse formation endothelial cell proliferation lens development in camera-type eye actin filament organization establishment or maintenance of cell polarity chemical synaptic transmission nervous system development protein localization cell proliferation positive regulation of cell proliferation regulation of cell shape actin filament polymerization peristalsis positive regulation of actin filament polymerization cortical actin cytoskeleton organization astral microtubule organization protein complex localization membrane raft organization regulation of myelination regulation of protein localization protein localization to synapse T cell proliferation T cell activation negative regulation of T cell proliferation regulation of membrane potential amyloid precursor protein metabolic process receptor clustering regulation of potassium ion transport positive regulation of potassium ion transport protein kinase B signaling cortical microtubule organization establishment or maintenance of epithelial cell apical/basal polarity GMP metabolic process GDP metabolic process reproductive structure development embryonic skeletal system morphogenesis tissue morphogenesis smooth muscle tissue development negative regulation of epithelial cell proliferation establishment of centrosome localization negative regulation of protein kinase B signaling hard palate development negative regulation of ERK1 and ERK2 cascade bicellular tight junction assembly protein localization to membrane protein localization to plasma membrane receptor localization to synapse cell-cell adhesion regulation of ventricular cardiac muscle cell action potential membrane repolarization during ventricular cardiac muscle cell action potential regulation of postsynaptic membrane neurotransmitter receptor levels maintenance of postsynaptic density structure neurotransmitter receptor localization to postsynaptic specialization membrane regulation of NIK/NF-kappaB signaling regulation of sodium ion transmembrane transport regulation of protein localization to synapse positive regulation of protein localization to plasma membrane regulation of potassium ion import negative regulation of p38MAPK cascade regulation of potassium ion export across plasma membrane protein localization to cell periphery negative regulation of G1/S transition of mitotic cell cycle cellular response to potassium ion anterograde axonal protein transport retrograde axonal protein transport establishment of planar polarity negative regulation of cell proliferation negative regulation of receptor internalization signal transduction positive regulation of cytosolic calcium ion concentration learning synaptic vesicle maturation social behavior locomotory exploration behavior establishment of protein localization regulation of long-term neuronal synaptic plasticity positive regulation of synaptic transmission neuromuscular process controlling balance dendritic spine morphogenesis protein-containing complex assembly vocalization behavior AMPA glutamate receptor clustering NMDA selective glutamate receptor signaling pathway positive regulation of neuron projection arborization positive regulation of excitatory postsynaptic potential regulation of grooming behavior T cell cytokine production cell adhesion single organismal cell-cell adhesion activation of protein kinase activity negative regulation of mitotic cell cycle nucleotide phosphorylation positive regulation of establishment of protein localization to plasma membrane positive regulation of multicellular organism growth positive regulation of developmental growth negative regulation of phosphatase activity sensory perception of pain neuronal ion channel clustering protein complex assembly regulation of N-methyl-D-aspartate selective glutamate receptor activity locomotory behavior response to cocaine regulation of neuronal synaptic plasticity embryo development
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Pedidos Plus Icon Minus Icon
          • Estatus del pedido
          • Ayuda para pedidos
          • Orden Rápida
          • Supply Center
          • eProcurement
          Soporte Plus Icon Minus Icon
          • Ayuda y soporte
          • Entre en Contacto
          • Centros de asistencia técnica
          • Consultar documentos y certificados
          • Informar de un problema en la web
          Recursos Plus Icon Minus Icon
          • Centros de aprendizaje
          • Promociones
          • Eventos & Webinars
          • Medios Sociales
          Acerca de Thermo Fisher Plus Icon Minus Icon
          • Acerca de nosotros Acerca de nosotros
          • Empleo Empleo
          • Inversores Inversores
          • Noticias Noticias
          • Responsabilidad social Responsabilidad social
          • Marcas comerciales
          • Políticas y avisos
          Nuestro Portafolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          Chile flag icon
          Chile

          Your items have has been added!


          Host server : magellan-search-blue-67655d8755-zsnhf:80/100.66.75.14:80.
          git-commit: dddaa802cd395f65bf1581942d0e97a089c38f41
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.46.0-Offline