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SAP97 Monoclonal Antibody (K64/15), FL650
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Product Details
75-030-FL650
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K64/15
Immunogen
Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli.
Conjugate
FL650
FL650
FL650
Excitation/Emission Max
655/676 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: discs large homolog 1, scribble cell polarity complex component; discs, large homolog 1; dJ1061C18.1.1; DKFZp761P0818; DKFZp781B0426; DLG1; E-dlg/SAP97; Drosophila discs-large tumor suppressor homologue (synapse associated protein); embryo-dlg/synapse-associated protein 97; presynaptic protein SAP97; synapse-associated protein 97; unnamed protein product
Gene Aliases: B130052P05Rik; DLGH1; E-dlg/SAP97; hdlg; mKIAA4187; SAP-97; SAP97
UniProt ID: (Human) Q12959, (Rat) Q62696, (Mouse) Q811D0
Entrez Gene ID: (Human) 1739, (Rat) 25252, (Mouse) 13383
guanylate kinase activity
phosphoprotein phosphatase activity
protein binding
cytoskeletal protein binding
potassium channel regulator activity
kinase binding
protein kinase binding
phosphatase binding
ionotropic glutamate receptor binding
ion channel binding
cadherin binding
binding, bridging
L27 domain binding
structural constituent of postsynaptic density
kinesin binding
enzyme binding
PDZ domain binding
negative regulation of transcription from RNA polymerase II promoter
endothelial cell proliferation
actin filament organization
establishment or maintenance of cell polarity
chemical synaptic transmission
nervous system development
regulation of cell shape
cortical actin cytoskeleton organization
astral microtubule organization
protein complex localization
regulation of protein localization
protein localization to synapse
regulation of membrane potential
receptor clustering
regulation of potassium ion transport
positive regulation of potassium ion transport
cortical microtubule organization
establishment or maintenance of epithelial cell apical/basal polarity
GMP metabolic process
GDP metabolic process
establishment of centrosome localization
negative regulation of ERK1 and ERK2 cascade
bicellular tight junction assembly
protein localization to membrane
protein localization to plasma membrane
receptor localization to synapse
cell-cell adhesion
regulation of ventricular cardiac muscle cell action potential
membrane repolarization during ventricular cardiac muscle cell action potential
regulation of postsynaptic membrane neurotransmitter receptor levels
maintenance of postsynaptic density structure
neurotransmitter receptor localization to postsynaptic specialization membrane
regulation of NIK/NF-kappaB signaling
regulation of sodium ion transmembrane transport
regulation of protein localization to synapse
positive regulation of protein localization to plasma membrane
regulation of potassium ion import
negative regulation of p38MAPK cascade
regulation of potassium ion export across plasma membrane
protein localization to cell periphery
negative regulation of G1/S transition of mitotic cell cycle
ureteric bud development
branching involved in ureteric bud morphogenesis
immunological synapse formation
lens development in camera-type eye
cell adhesion
protein localization
positive regulation of cell proliferation
positive regulation of gene expression
epithelial structure maintenance
cerebral cortex development
peristalsis
positive regulation of actin filament polymerization
membrane raft organization
regulation of myelination
activation of protein kinase activity
T cell activation
negative regulation of T cell proliferation
amyloid precursor protein metabolic process
reproductive structure development
embryonic skeletal system morphogenesis
tissue morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
negative regulation of protein kinase B signaling
hard palate development
cellular response to brain-derived neurotrophic factor stimulus
positive regulation of multicellular organism growth
positive regulation of developmental growth
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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