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Antibodies Inc
SCG10/Stathmin-2 Monoclonal Antibody (L5/1), FL490
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Product Details
75-063-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
L5/1
Immunogen
Synthetic peptide 155-179 C-terminus of rat SCG10 (ERLQEKERHAAEVRRNKELQVELSG; accession number P21818).
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
STMN2, also known as SCG-10, is a neuronal growth-associated protein that shares significant amino acid sequence similarity with the phosphoprotein stathmin. STMN2 may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neuron-specific growth-associated protein; neuronal growth-associated protein (silencer element); Protein SCG10; SGC10; Stathmin-2; stathmin-like 2; superior cervical ganglia, neural specific 10; Superior cervical ganglion-10 protein; superiorcervical ganglia, neural specific 10
Gene Aliases: AI159727; SCG10; SCGN10; Stmb2; STMN2
UniProt ID: (Human) Q93045, (Rat) P21818, (Mouse) P55821
Entrez Gene ID: (Human) 11075, (Rat) 84510, (Mouse) 20257
negative regulation of microtubule depolymerization
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of microtubule polymerization
positive regulation of microtubule depolymerization
cellular response to nerve growth factor stimulus
microtubule depolymerization
neuron projection development
regulation of cytoskeleton organization
regulation of microtubule polymerization or depolymerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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