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Antibodies Inc
Kir2.3 K+ Channel Monoclonal Antibody (N25/35), FL490
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Product Details
75-069-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N25/35
Immunogen
Fusion protein amino acids 390-445 of human Kir2.3 (accession number NP_032453) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BIR11; Brain inwardly rectifying K(+) channel 2; Hippocampal inward rectifier; hippocampal inward rectifier potassium channel; HIR; HIRK2; HRK1; Inward rectifier K(+) channel Kir2.3; inward rectifier potassium channel; Inward rectifier potassium channel 4; IRK-3; IRK3; KCNJ4; Kir 2.3; Potassium channel, inwardly rectifying subfamily J member 4; potassium channel, inwardly rectifying subfamily J, member 4; potassium inwardly-rectifying channel, subfamily J, member 4; potassium voltage-gated channel subfamily J member 4
Gene Aliases: HIR; HIRK2; HRK1; IRK-3; IRK3; Kcnf2; KCNJ4; Kir2.3; MB-IRK3
UniProt ID: (Human) P48050, (Rat) P52190
Entrez Gene ID: (Human) 3761, (Mouse) 16520, (Rat) 116649
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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