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Antibodies Inc
GABA-B-R2 Monoclonal Antibody (N81/2), FL490
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Product Details
75-124-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N81/2
Immunogen
Fusion protein amino acids 861-912 of rat GABABR2 (accession number NP_113990) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ36928; G protein-coupled receptor 51; G-protein coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABA-B-R2; GABA-BR2; GABABR2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; Gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; HG20; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1
Gene Aliases: GABABR2; GABBR2; Gb2; Gm425; GPR51; GPRC3B; HG20; HRIHFB2099
UniProt ID: (Human) O75899, (Rat) O88871, (Mouse) Q80T41
Entrez Gene ID: (Human) 9568, (Rat) 83633, (Mouse) 242425
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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