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Thorase/Atad1 Monoclonal Antibody (N125/10), FL594
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Product Details
75-157-FL594
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N125/10
Immunogen
Fusion protein amino acids 1-361 (full-length) of mouse Thorase (accession number Q9D5T0) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
594/615 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AAA+ ATPase Thorase; ATPase family AAA domain-containing protein 1; ATPase Thorase; FLJ14600; hATAD1; Neuroprotective protein 6; Outer mitochondrial transmembrane helix translocase; Thorase; unnamed protein product
Gene Aliases: 4921525H23Rik; Ab2-088; AFDC1; ATAD1; AW107648; FNP001; hATAD1; HKPX4; Msp1; Npg6; THORASE
UniProt ID: (Human) Q8NBU5, (Mouse) Q9D5T0, (Rat) Q505J9
Entrez Gene ID: (Human) 84896, (Mouse) 67979, (Rat) 309532
positive regulation of receptor internalization
learning
memory
cytoplasmic microtubule organization
negative regulation of synaptic transmission, glutamatergic
regulation of postsynaptic neurotransmitter receptor internalization
extraction of mislocalized protein from mitochondrial outer membrane
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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