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Antibodies Inc
Pan-Gamma-Protocadherin Monoclonal Antibody (N159/5), FL550
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Product Details
75-185-FL550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N159/5
Immunogen
Fusion protein corresponding to amino acids 808-931 (C-terminal cytoplasmic constant domain) of mouse Gamma-protocadherin-A1 that is shared by all 22 Gamma-protocadherins (A subfamily amino acids ~807-930, B subfamily amino acids ~789-912 and C subfamily amino acids ~818-941); produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
550/575 nm
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3' RACE product; Pan-Gamma-Protocadherin-A; PCDH gamma A; PCDH-gamma-A; PCDH-gamma-A4; PCDHGA; pcdhga4; protocadherin 13; protocadherin 2; protocadherin gamma A12; protocadherin gamma B2; protocadherin gamma B6; protocadherin gamma C-VI; protocadherin gamma subfamily A, 12; protocadherin gamma subfamily C, 3; protocadherin gamma-A1; protocadherin gamma-A10; protocadherin gamma-A11; protocadherin gamma-A2; protocadherin gamma-A3; Protocadherin gamma-A4; protocadherin gamma-A5; protocadherin gamma-A6; protocadherin gamma-A7; protocadherin gamma-A8; protocadherin gamma-A9; protocadherin gamma-B1; protocadherin gamma-B2; protocadherin gamma-B4; protocadherin gamma-B5; protocadherin gamma-B6; protocadherin gamma-B7; protocadherin gamma-C4; protocadherin gamma-C5
Gene Aliases: mKIAA0588; mKIAA4054; pc2c; PC43; Pcdh13; Pcdh2; Pcdhga4
UniProt ID: (Mouse) Q91XY4
Entrez Gene ID: (Mouse) 93709, (Mouse) 93722, (Mouse) 93723, (Mouse) 93724, (Mouse) 93710, (Mouse) 93711, (Mouse) 93712, (Mouse) 93713, (Mouse) 93714, (Mouse) 93715, (Mouse) 93716, (Mouse) 93717, (Mouse) 93699, (Mouse) 93700, (Mouse) 93701, (Mouse) 93702, (Mouse) 93703, (Mouse) 93704, (Mouse) 93706, (Mouse) 93707, (Mouse) 93708
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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