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Antibodies Inc
Frataxin Monoclonal Antibody (N191/7), FL550
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Product Details
75-207-FL550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N191/7
Immunogen
Fusion protein amino acids 81-210 (C-terminus) of human Frataxin (accession number Q16595) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
550/575 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Frataxin, mitochondrial; Friedreich ataxia protein; Fxn
Gene Aliases: CyaY; FA; FARR; FRDA; FXN; X25
UniProt ID: (Human) Q16595
Entrez Gene ID: (Human) 2395
oxidative phosphorylation
heme biosynthetic process
ion transport
iron ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
iron-sulfur cluster assembly
protein autoprocessing
proprioception
cellular cation homeostasis
mitochondrial respiratory chain complex III assembly
organ growth
regulation of growth
negative regulation of multicellular organism growth
negative regulation of apoptotic process
[2Fe-2S] cluster assembly
[4Fe-4S] cluster assembly
negative regulation of organ growth
muscle cell cellular homeostasis
positive regulation of lyase activity
protein maturation
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria
inorganic ion homeostasis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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