Search
Antibodies Inc
Arl13b Monoclonal Antibody (N295B/66)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 12
Arl13b Antibody (75-287) in ICC/IF
Ciliogenesis induced mIMCD3 cells stably expressing eGFP-UBL3 WT (upper panel – arrows inside and at base of cilium) and eGFP-UBL3 C>A (middle panel – arrowheads at basal bodies/centromeres), and transiently expressing eGFP-UBL3 S>K (bottom panel – arrows inside cilium). Cilia stained with antibodies against ARL13B (Product # 75-287, 1:500; magenta). Basal bodies stained with antibodies against pericentrin (PCTN, red). Nuclei stained with DAPI (blue). Image from publication CC-BY-4.0. PMID:36672247.
Product Details
75-287
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat,
Zebrafish
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
N295B/66
Immunogen
Fusion protein amino acids 208-427 (C-terminus) of mouse Arl13b (accession number Q640N2) produced recombinantly in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ADP ribosylation factor like GTPase 13B; ADP-ribosylation factor-like 2-like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; Protein hennin; Protein scorpion; scorpion; un-named hi459; unm hi459; unnamed protein product
Gene Aliases: A530097K21Rik; A930014M17Rik; ARL13B; ARL2L1; C530009C10Rik; chunp6872; fc23g07; hnn; JBTS8; wu:fc23g07; zgc:123149
UniProt ID: (Human) Q3SXY8, (Mouse) Q640N2, (Zebrafish) Q8JHI3
Entrez Gene ID: (Human) 200894, (Rat) 304037, (Mouse) 68146, (Zebrafish) 286784
smoothened signaling pathway
multicellular organism development
neural tube patterning
interneuron migration from the subpallium to the cortex
formation of radial glial scaffolds
photoreceptor cell outer segment organization
cilium morphogenesis
receptor localization to nonmotile primary cilium
non-motile cilium assembly
heart looping
determination of left/right symmetry
dorsal/ventral pattern formation
left/right axis specification
small GTPase mediated signal transduction
nonmotile primary cilium assembly
cilium assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support