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Ankyrin-R/G Monoclonal Antibody (N388A/27), FL550

View all (5) Ankyrin 1/3 antibodies

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Ankyrin-R/G Monoclonal Antibody (N388A/27), FL550

Product Details

75-415-FL550

Applications
Tested Dilution
Publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

N388A/27

Immunogen

Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R (accession number P16157) produced recombinantly in E. Coli.
3D Epitope / Immunogen

Conjugate

FL550 FL550 FL550

Excitation/Emission Max

550/575 nm

Form

Liquid

Concentration

0.5 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Dry ice (international)

Product Specific Information

For maximum recovery of product, centrifuge the vial prior to removing the cap.

Target Information

Ankyrin 1 and Ankyrin 3 are members of the ankyrin family of proteins, which are crucial for the stability and functionality of the cellular membrane and the organization of membrane-associated proteins. Both Ankyrin 1 and Ankyrin 3 are integral to maintaining the structure and functionality of cellular membranes and have significant roles in health and disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ANK-1; ANK-3; ankyrin 1, erythrocytic; ankyrin 1, erythroid; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, node of Ranvier (ankyrin G); Ankyrin-1; Ankyrin-3; Ankyrin-G; Ankyrin-R; Attaches integral membrane proteins to cytoskeletal elements; brain-specific ankyrin-G; Erythrocyte ankyrin; normoblastic anemia; unnamed protein product

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Gene Aliases: 2900054D09Rik; AI314020; ANK; Ank-1; ANK-3; ANK1; ANK3; AnkG; ankyrin-1; Ankyrin-3; ANKYRIN-G; MRT37; nb; pale; SPH1; SPH2

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UniProt ID: (Human) P16157, (Human) Q12955, (Mouse) Q02357, (Rat) O70511, (Mouse) G5E8K5

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Entrez Gene ID: (Human) 286, (Human) 288, (Mouse) 11733, (Rat) 306570, (Rat) 361833, (Mouse) 11735

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Function(s)
structural molecule activity structural constituent of cytoskeleton protein binding cytoskeletal adaptor activity enzyme binding protein phosphatase binding spectrin binding ion channel binding ATPase binding cytoskeletal protein binding sodium channel regulator activity protein binding, bridging cadherin binding channel activator activity scaffold/adaptor protein
Process(es)
exocytosis ER to Golgi vesicle-mediated transport cytoskeleton organization signal transduction positive regulation of organelle organization maintenance of epithelial cell apical/basal polarity Golgi vesicle transport protein localization to plasma membrane mitotic cytokinesis plasma membrane organization axonogenesis neuromuscular junction development positive regulation of gene expression positive regulation of cell communication by electrical coupling positive regulation of sodium ion transport magnesium ion homeostasis neuronal action potential positive regulation of homotypic cell-cell adhesion Golgi to plasma membrane protein transport regulation of potassium ion transport establishment of protein localization positive regulation of membrane potential cellular response to magnesium ion membrane assembly maintenance of protein location in plasma membrane positive regulation of protein targeting to membrane protein localization to axon positive regulation of membrane depolarization during cardiac muscle cell action potential negative regulation of delayed rectifier potassium channel activity porphyrin-containing compound biosynthetic process monovalent inorganic cation transport erythrocyte development iron ion homeostasis protein targeting to plasma membrane axon guidance synapse organization positive regulation of sodium ion transmembrane transporter activity positive regulation of cation channel activity positive regulation of action potential
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