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Antibodies Inc
Kir2.4 Monoclonal Antibody (N465/11), FL490
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Product Details
75-471-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N465/11
Immunogen
Fusion protein amino acids 360-434 (cytoplasmic C-terminus) of mouse Kir2.4 (accession number Q8JZN3) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-sensitive inward rectifier potassium channel 14; Inward rectifier K(+) channel Kir2.4; inwardly rectifying potassium channel Kir2.4; IRK-4; IRK4; Potassium channel, inwardly rectifying subfamily J member 14; potassium inwardly-rectifying channel J14; potassium inwardly-rectifying channel, subfamily J, member 14
Gene Aliases: A930026G01Rik; IRK4; Kcnj14; Kir2.4
UniProt ID: (Rat) O70596, (Mouse) Q8JZN3
Entrez Gene ID: (Rat) 276720, (Mouse) 211480
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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